Characterization of epitope specificities of reference antibodies used for the quantification of the birch pollen allergen Bet v 1

S. Brier; M. Le Mignon; K. Jain; C. Lebrun; F. Peurois; C. Kellenberger; V. Bordas-Le Floch; L. Mascarell; E. Nony; P. Moingeon

doi:10.1111/all.13364

Journal articles

Characterization of epitope specificities of reference antibodies used for the quantification of the birch pollen allergen Bet v 1

S. Brier ¹ M. Le Mignon ¹ K. Jain ¹ C. Lebrun ¹ F. Peurois ¹ C. Kellenberger ² V. Bordas-Le Floch ¹ L. Mascarell ¹ E. Nony ¹ P. Moingeon ¹

1 Stallergenes Greer (France, Antony)

2 AFMB - Architecture et fonction des macromolécules biologiques

Abstract : Accurate allergen quantification is needed to document the consistency of allergen extracts used for immunotherapy. Herein, we characterize the epitope specificities of two monoclonal antibodies used in an ELISA for the quantification of the major birch pollen allergen Bet v 1, established as a reference by the BSP090 European project.

Keywords : epitope mapping Bet v 1 isoforms ELISA 5B4 6H4

Document type :

Journal articles

Domain :

Life Sciences [q-bio] / Biochemistry, Molecular Biology / Biomolecules [q-bio.BM]

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https://hal-amu.archives-ouvertes.fr/hal-02095085
Contributor : Yves Bourne <>
Submitted on : Wednesday, April 10, 2019 - 11:13:19 AM
Last modification on : Tuesday, March 17, 2020 - 2:01:26 AM

Characterization of epitope specificities of reference antibodies used for the quantification of the birch pollen allergen Bet v 1

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Characterization of epitope specificities of reference antibodies used for the quantification of the birch pollen allergen Bet v 1

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