Stromal myofibroblasts are drivers of invasive cancer growth, Int J Cancer, vol.123, issue.10, pp.2229-2267, 2008. ,
Cancer-associated fibroblast-derived annexin A6+ extracellular vesicles support pancreatic cancer aggressiveness, J Clin Invest, vol.126, issue.11, pp.4140-56, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01408056
Stromal cues regulate the pancreatic cancer epigenome and metabolome, Proc Natl Acad Sci U S A, vol.114, issue.5, pp.1129-1163, 2017. ,
Exploring metabolic configurations of single cells within complex tissue microenvironments, Cell Metab, vol.26, issue.5, pp.788-800, 2017. ,
Molecular pathways: trafficking of metabolic resources in the tumor microenvironment, Clin Cancer Res, vol.21, issue.4, pp.680-686, 2015. ,
The reverse Warburg effect is likely to be an Achilles' heel of cancer that can be exploited for cancer therapy, Oncotarget, vol.8, issue.34, pp.57813-57838, 2017. ,
Cancer metabolism in space and time: beyond the Warburg effect, Biochim Biophys Acta, issue.8, pp.556-72, 2017. ,
Reciprocal metabolic reprogramming through lactate shuttle coordinately influences tumor-stroma interplay, Cancer Res, vol.72, pp.5130-5170, 2012. ,
Cancer-associated fibroblasts enhance pancreatic cancer cell invasion by remodeling the metabolic conversion mechanism, Oncol Rep, vol.37, issue.4, pp.1971-1980, 2017. ,
Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion, Nature, vol.536, issue.7617, pp.479-83, 2016. ,
Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2,3-dioxygenase promotes breast cancer progression, Breast Cancer Res, vol.16, issue.4, p.410, 2014. ,
Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth, Semin Cancer Biol, vol.25, pp.47-60, 2014. ,
Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism, Elife, vol.5, p.10250, 2016. ,
Impact of tumor microenvironment and epithelial phenotypes on metabolism in breast cancer, Clin Cancer Res, vol.19, issue.3, pp.571-85, 2013. ,
Targeting stromal glutamine synthetase in tumors disrupts tumor microenvironmentregulated cancer cell growth, Cell Metab, vol.24, issue.5, pp.685-700, 2016. ,
Exo-MFAa 13C metabolic flux analysis framework to dissect tumor microenvironmentsecreted exosome contributions towards cancer cell metabolism, Metab Eng, pp.156-72, 2017. ,
Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma, Proc Natl Acad Sci U S A, vol.110, issue.10, pp.3919-3943, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-01460466
Lactate metabolism in human lung tumors, Cell, vol.171, issue.2, 2017. ,
Metabolic symbiosis enables adaptive resistance to anti-angiogenic therapy that is dependent on mTOR signaling, Cell Rep, vol.15, issue.6, pp.1144-60, 2016. ,
Metabolic interactions in the tumor microenvironment, Trends Cell Biol, vol.27, issue.11, pp.863-75, 2017. ,
Coupling between the circadian clock and cell cycle oscillators: implication for healthy cells and malignant growth, Front Neurol, vol.6, p.96, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01255098
Clock regulation of metabolites reveals coupling between transcription and metabolism, Cell Metab, vol.25, issue.4, pp.961-74, 2017. ,
Systems chronotherapeutics, Pharmacol Rev, vol.69, issue.2, pp.161-99, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-00780810
Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells, Nature, vol.497, issue.7451, pp.633-640, 2013. ,
Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors, Nat Med, vol.23, issue.2, pp.235-276, 2017. ,
Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein, Cancer Res, vol.75, issue.3, pp.544-53, 2015. ,
Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions, Nat Commun, vol.8, p.16031, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01788014
Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress, Cancer Cell, vol.27, issue.1, pp.57-71, 2015. ,
Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress, Cell Res, vol.26, issue.10, pp.1112-1142, 2016. ,
Metabolic rewiring by oncogenic BRAF V600E links ketogenesis pathway to BRAF-MEK1 signaling, Mol Cell, vol.59, issue.3, pp.345-58, 2015. ,
Prevention of dietary-fatfueled ketogenesis attenuates BRAF V600E tumor growth, Cell Metab, vol.25, issue.2, pp.358-73, 2017. ,
Adipocytes promote malignant growth of breast tumours with monocarboxylate transporter 2 expression via beta-hydroxybutyrate, Nat Commun, vol.8, p.14706, 2017. ,
Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass, Science, vol.358, issue.6365, pp.941-947, 2017. ,
Tumors as organs: complex tissues that interface with the entire organism, Dev Cell, vol.18, issue.6, pp.884-901, 2010. ,
Desmoplasia in primary tumors and metastatic lesions of pancreatic cancer, Clin Cancer Res, vol.21, issue.15, pp.3561-3569, 2015. ,
Breast cancer-derived lung metastases show increased pyruvate carboxylase-dependent anaplerosis, Cell Rep, vol.17, issue.3, pp.837-885, 2016. ,
Extracellular metabolic energetics can promote cancer progression, Cell, vol.160, issue.3, pp.393-406, 2015. ,
Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis, Nat Genet, vol.49, issue.3, pp.367-76, 2017. ,
Breastcancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis, Nat Cell Biol, vol.17, issue.2, pp.183-94, 2015. ,