STEEx, a boundary between the world of quiescence and the vegetative cycle - Aix-Marseille Université Accéder directement au contenu
Article Dans Une Revue Current Genetics Année : 2018

STEEx, a boundary between the world of quiescence and the vegetative cycle

Résumé

Telomere maintenance mechanism is poorly studied in quiescence, a reversible non-proliferative state. We previously described in fission yeast a new mode of repair of telomeres named STEEx, that specifically operates in post-mitotic cells harboring eroded telomeres. This mechanism, promoted by transcription-induced telomeric recombination, prevents cells to exit properly from quiescence, suggesting that STEEx act as an anti-proliferative barrier. Here, we further showed that STEEx are genetically controlled by the Tel1(ATM)- and Rad3(ATR)- dependent DDR pathways. We discussed the possibility that STEEx represent a boundary between quiescence and vegetative cycle.
Fichier non déposé

Dates et versions

hal-02143607 , version 1 (29-05-2019)

Identifiants

Citer

Laetitia Maestroni, Vincent Geli, Stephane Coulon. STEEx, a boundary between the world of quiescence and the vegetative cycle. Current Genetics, 2018, 64 (4), pp.901-905. ⟨10.1007/s00294-018-0808-x⟩. ⟨hal-02143607⟩

Collections

CNRS UNIV-AMU CRCM
24 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More