Evolution of patients’ socio-behavioral characteristics in the context of DAA: Results from the French ANRS CO13 HEPAVIH cohort of HIV-HCV co-infected patients

Issifou Yaya (1) , Perrine Roux (1) , Fabienne Marcellin (1) , Linda Wittkop (2) , Laure Esterle (2) , Bruno Spire (1) , Stéphanie Domínguez (3, 4) , Boni Armand Elegbe (1) , Lionel Piroth (5) , Philippe Sogni (6) , Dominique Salmon-Céron (7) , Maria Patrizia Carrieri (1)

1 SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD - Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale
2 BPH - Bordeaux population health
3 DILTEC - DILTEC - Didactique des langues, des textes et des cultures - EA 2288
4 Inserm U955, équipe 16 - GHU A. Chenevier - Henri Mondor
5 Département d'infectiologie (CHU de Dijon)
6 Service d'hépatologie médicale [CHU Cochin]
7 CIC - Biotherapie - AP-HP (cochin - Pasteur)

Direct-acting antivirals (DAA) have dramatically increased HCV cure rates with minimal toxicity in HIV-HCV co-infected patients. This study aimed to compare the socio-behavioral characteristics of patients initiating pegylated-interferon (PEG-IFN)-based HCV treatment with those of patients initiating DAA-based treatment.

Keywords: Hepatitis C virus; Cannabis; Drug therapy; Alcohol consumption; Drug users; France; Liver fibrosis; Chronic hepatitis

Domains: Life Sciences [q-bio]; Santé publique et épidémiologie

Issifou Yaya, Perrine Roux, Fabienne Marcellin, Linda Wittkop, Laure Esterle, et al.. Evolution of patients’ socio-behavioral characteristics in the context of DAA: Results from the French ANRS CO13 HEPAVIH cohort of HIV-HCV co-infected patients. PLoS ONE, 2018, 13 (7), pp.e0199874. ⟨10.1371/journal.pone.0199874⟩. ⟨hal-02146246⟩