Skip to Main content Skip to Navigation
Journal articles

Possible functionality of start and stop codons present at specific and conserved positions in animal mitochondrial genes specifying tRNA

Abstract : Several metazoan mitochondrial-trn genes (specifying tRNA) exhibit nucleotide triplets at specific and conserved positions corresponding to stop codons (TAG/TAA) and/or start codons (ATG/ATA). The products of these genes, which bear one or two types of these codons are called ss-tRNAs (for stop/start). In this article, several examples of ss-trn genes bearing start or stop codons in metazoans (protostomes and deuterostomes) strongly suggest that these codons are functional. Moreover, the ss-trn genes found in apicoplast genomes likely have a mitochondrial origin, but the TAR and ATR triplets (R for purines) found in their sequences seem to play only a structural role. Future investigations should attempt to clarify the mechanisms of the transcription and maturation of ss-trn genes with their overlapping protein genes and the possible regulatory roles of stop and start codons found in trn sequences.
Complete list of metadatas

Cited literature [23 references]  Display  Hide  Download

https://hal-amu.archives-ouvertes.fr/hal-02151814
Contributor : Eric Faure <>
Submitted on : Monday, June 10, 2019 - 12:44:07 PM
Last modification on : Thursday, January 23, 2020 - 6:22:13 PM

File

Faure 2019 Possible functional...
Publisher files allowed on an open archive

Licence


Distributed under a Creative Commons Attribution - NonCommercial - ShareAlike 4.0 International License

Identifiers

  • HAL Id : hal-02151814, version 1

Collections

Citation

Eric Faure, Roxane-Marie Barthelemy. Possible functionality of start and stop codons present at specific and conserved positions in animal mitochondrial genes specifying tRNA. International Journal of Zoology Studies, International Journal of Zoology Studies (IJZS), 2019. ⟨hal-02151814⟩

Share

Metrics

Record views

102

Files downloads

202