Strategy focused on clinical parameters of microcirculation to resuscitate patients in septic shock: Do not forget any tools

Saber Davide Barbar 1 Laurent Muller Vincent Bruckert 2 Marc Léone 3 Mervyn Singer 4
1 EA 2992 - Caractéristiques féminines des dysfonctions des interfaces cardio-vasculaires
2 Service d'anesthésie et de réanimation [CHU Pitié-Salpêtrière]
3 MEPHI - Microbes évolution phylogénie et infections
4 UCL - University College of London [London]
Abstract : Editorial Strategy focused on clinical parameters of microcirculation to resuscitate patients in septic shock: Do not forget any tools The current objective of initial resuscitation of patients with septic shock is the optimisation of general haemodynamic variables including heart rate, mean arterial blood pressure, cardiac output and cardiac preload using normalisation of arterial lactate as a marker of presumed success. However, microcirculatory blood flow can remain impaired despite restoration of macro-haemodynamic parameters. Ait-Oufella et al. clearly showed that persistence of skin mottling], an increased capillary refill time (CRT) and an increased toe-to-room temperature gradient were associated with worse patient outcomes. Similarly, Leone et al. reported that low oxygen tissue saturation (StO 2) was associated with poor outcomes in patients with septic shock. Few studies have assessed a strategy targeting the microcirculation...
Keywords : ICU Septic shock Microcirculation
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Saber Davide Barbar, Laurent Muller, Vincent Bruckert, Marc Léone, Mervyn Singer. Strategy focused on clinical parameters of microcirculation to resuscitate patients in septic shock: Do not forget any tools. Anaesthesia Critical Care & Pain Medicine, Elsevier Masson, 2019, 38 (3), pp.209-210. ⟨10.1016/j.accpm.2019.04.011⟩. ⟨hal-02159362⟩

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