, Mol Microbiol, vol.27, pp.807-818

D. G. Lee, J. M. Urbach, G. Wu, N. T. Liberati, R. L. Feinbaum et al.,

M. , D. E. Friedman, L. Li, L. Grills, G. Montgomery et al., Ausubel 605 FM, Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial, 2006.

, Genome Biol, vol.14

H. Mikkelsen, R. Mcmullan, and A. Filloux, The Pseudomonas aeruginosa Reference Strain 608 PA14 Displays Increased Virulence Due to a Mutation in ladS, PLoS ONE, vol.6, p.29113, 2011.

I. Ventre, A. L. Goodman, I. Vallet-gely, P. Vasseur, C. Soscia et al., , p.610

S. Lory and A. Filloux, Multiple sensors control reciprocal expression of Pseudomonas 611 aeruginosa regulatory RNA and virulence genes, Proc Natl Acad Sci, vol.103, pp.171-176, 2006.

G. Chambonnier, L. Roux, D. Redelberger, F. Fadel, A. Filloux et al., , p.613

C. Bordi, The Hybrid Histidine Kinase LadS Forms a Multicomponent Signal 614, 2016.

, Transduction System with the GacS/GacA Two-Component System in Pseudomonas 615 aeruginosa, PLOS Genet, vol.12, p.1006032

L. P. Allsopp, T. E. Wood, S. A. Howard, F. Maggiorelli, L. M. Nolan et al., , 2017.

J. Klockgether, A. Munder, J. Neugebauer, C. F. Davenport, F. Stanke et al.,

U. Pohl, T. M. Wiehlmann, L. Tummler, and B. , Genome Diversity of Pseudomonas aeruginosa 628 PAO1 Laboratory Strains, J Bacteriol, vol.192, pp.1113-1121, 2010.

A. Dötsch, C. Pommerenke, F. Bredenbruch, R. Geffers, and S. Häussler, Evaluation of a 630 microarray-hybridization based method applicable for discovery of single nucleotide 631 polymorphisms (SNPs) in the Pseudomonas aeruginosa genome, BMC Genomics, vol.10, p.29, 2009.

S. Jayaseelan, D. Ramaswamy, and S. Dharmaraj, Pyocyanin: production, applications, 633 challenges and new insights, World J Microbiol Biotechnol, vol.30, pp.1159-1168, 2014.

F. Jiang, N. R. Waterfield, J. Yang, G. Yang, and J. Q. , A Pseudomonas aeruginosa Type VI, 2014.

, Secretion Phospholipase D Effector Targets Both Prokaryotic and Eukaryotic Cells, Cell Host 636 Microbe, vol.15, pp.600-610

T. G. Sana, C. Baumann, A. Merdes, C. Soscia, T. Rattei et al., Filloux system effector delivery mechanism dependent on PAAR and a chaperone-co-chaperone 651 complex, Nat Microbiol, vol.3, pp.632-640

S. Bleves, Game of Trans-Kingdom Effectors, Trends Microbiol, vol.24, pp.773-774, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01766104

S. Bleves, V. Viarre, R. Salacha, G. Michel, A. Filloux et al., Protein secretion 654 systems in Pseudomonas aeruginosa: A wealth of pathogenic weapons, Int J Med Microbiol, vol.655, pp.534-543, 2010.

S. Bleves, A. Lazdunski, and A. Filloux, Membrane topology of three Xcp proteins involved in 657 exoprotein transport by Pseudomonas aeruginosa, J Bacteriol, vol.178, pp.4297-4300, 1996.

B. Douzi, G. Ball, C. Cambillau, M. Tegoni, and R. Voulhoux, , p.659, 2011.

, Pseudomonas aeruginosa Type II Secretion Machinery through Multiple Interactions with

. Substrates, J Biol Chem, vol.286, pp.40792-40801

B. Douzi, N. Trinh, S. Michel-souzy, A. Desmyter, G. Ball et al., Identification of Virulence Genes in a Pathogenic Strain of Pseudomonas aeruginosa by 673 Representational Difference Analysis, J Bacteriol, vol.184, pp.952-961

M. Tan, S. Mahajan-miklos, and F. M. Ausubel, Killing of Caenorhabditis elegans by, 1999.

, Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis, Proc Natl Acad Sci, vol.676, pp.715-720

S. Chugani, B. S. Kim, S. Phattarasukol, M. J. Brittnacher, S. H. Choi et al., Strain-dependent diversity in the Pseudomonas aeruginosa quorum-sensing regulon, vol.678

, Natl Acad Sci, vol.109, pp.2823-2831

T. G. Sana, A. Laubier, and S. Bleves, Gene Transfer: Conjugation, Filloux, A, p.681, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01458210

, Pseudomonas Methods and Protocols

D. A. Benson, K. Clark, I. Karsch-mizrachi, D. J. Lipman, J. Ostell et al., , 2014.

, Nucleic Acids Res, vol.42, pp.32-37

B. Langmead, C. Trapnell, M. Pop, S. L. Salzberg, D. W. Essar et al., Identification and characterization of genes 695 for a second anthranilate synthase in Pseudomonas aeruginosa: interchangeability of the two 696 anthranilate synthases and evolutionary implications, J Bacteriol, vol.172, pp.884-900, 1990.

I. Vallet, J. W. Olson, S. Lory, A. Lazdunski, and A. Filloux, The chaperone/usher pathways of 698 Pseudomonas aeruginosa: Identification of fimbrial gene clusters (cup) and their involvement in 699 biofilm formation, Proc Natl Acad Sci, vol.98, pp.6911-6916, 2001.

C. Bordi, M. Lamy, I. Ventre, E. Termine, A. Hachani et al., , p.701

A. Lazdunski and A. Filloux, Regulatory RNAs and the HptB/RetS signalling pathways fine-702 tune Pseudomonas aeruginosa pathogenesis: P. aeruginosa signalling via HptB, RetS and sRNA, 2010.

, Mol Microbiol, vol.76, pp.1427-1443

C. Soscia, A. Hachani, A. Bernadac, A. Filloux, and S. Bleves, Cross Talk between Type III 705 Secretion and Flagellar Assembly Systems in Pseudomonas aeruginosa, J Bacteriol, vol.189, p.3124, 2007.

D. H. Figurski and D. R. Helinski, Replication of an Origin-Containing Derivative of Plasmid 708 RK2 Dependent on a Plasmid Function Provided in Trans, Proc. Natl. Acad. Sci, vol.76, issue.4, pp.1648-709, 1979.

K. Kaniga, I. Delor, and G. R. Cornelis, A Wide-Host-Range Suicide Vector for Improving, 1991.

, PBAD promoter of pTS51 encoding qslA. **, P <0.01, *, P <0.05 and NS