Resveratrol improves mitochondrial energetic pathway and endothelial function in type 2 diabetic female rat heart submitted to ischemia-reperfusion injury

N. Fourny (1) , C. Lan (1) , E. Seree (2) , M. Bernard (1) , Martine Desrois (1)

1 CRMBM - Centre de résonance magnétique biologique et médicale
2 C2VN - Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research

Type 2 diabetic women present high risk of mortality by cardiovascular (CV) disease in comparison to non-diabetic women. Most of anti-diabetic treatments do not decrease patient’s CV mortality, therefore new approaches need to be found. Resveratrol (RSV) is a polyphenol found in grapes reported to be beneficial on oxidative stress, endothelial dysfunction andinflammation involved in CV complications of T2D.

Domains: Life Sciences [q-bio]

N. Fourny, C. Lan, E. Seree, M. Bernard, Martine Desrois. Resveratrol improves mitochondrial energetic pathway and endothelial function in type 2 diabetic female rat heart submitted to ischemia-reperfusion injury. Archives of Cardiovascular Diseases Supplements, 2019, Archives of Cardiovascular Diseases Supplements, 11 (2), pp.219. ⟨hal-02373457⟩