Proamyloidogenic effects of membrane type 1 matrix metalloproteinase involve MMP-2 and BACE-1 activities, and the modulation of APP trafficking

Jean-Michel Paumier (1) , Nathalie Py (1) , Laura García-González (1) , Anne Bernard (1) , Delphine Stephan (1) , Laurence Louis (1) , Frédéric Checler (2) , Michel Khrestchatisky (1) , Kévin Baranger (1) , Santiago Rivera (1)

1 INP - Institut de neurophysiopathologie
2 IPMC - Institut de pharmacologie moléculaire et cellulaire

Domaines: Neurosciences [q-bio.NC]

Jean-Michel Paumier, Nathalie Py, Laura García-González, Anne Bernard, Delphine Stephan, et al.. Proamyloidogenic effects of membrane type 1 matrix metalloproteinase involve MMP-2 and BACE-1 activities, and the modulation of APP trafficking. FASEB Journal, 2019, 33 (2), pp.2910-2927. ⟨10.1096/fj.201801076R⟩. ⟨hal-02387988⟩