, Diagnostic and statistical manual of mental disorders DSM-5. American psychiatric association, APA, 2013.

G. Arriaga and E. D. Jarvis, Mouse vocal communication system: are ultrasounds learned or innate?, Brain and language, vol.124, issue.1, pp.96-116, 2013.

K. C. Berridge, J. W. Aldridge, K. R. Houchard, and X. Zhuang, Sequential super-stereotypy of an instinctive fixed action pattern in hyper-dopaminergic mutant mice: a model of obsessive compulsive disorder and Tourette's, BMC biology, vol.34, 2005.

S. L. Bishop, J. Richler, and C. Lord, Association between restricted and repetitive behaviors and nonverbal IQ in children with autism spectrum disorders, childhood and adolescence, vol.12, issue.4-5, pp.247-267, 2006.

J. W. Bodfish, F. J. Symons, D. E. Parker, and M. H. Lewis, Varieties of repetitive behavior in autism: comparisons to mental retardation, Journal of autism and developmental disorders, vol.30, issue.3, pp.237-243, 2000.

A. Boomsma, N. D. Van-lang, D. Jonge, M. V. , D. Bildt et al., A new symptom model for autism cross-validated in an independent sample, vol.49, pp.809-816, 2008.

S. Cangur, H. Ankarali, and O. Pasin, Comparing Performances of Multiple Comparison Methods in Commonly Used 2 x C Contingency Tables. Interdisciplinary sciences, computational life sciences, vol.8, pp.337-345, 2016.

X. Caubit, P. Gubellini, J. Andrieux, P. L. Roubertoux, M. Metwaly et al., TSHZ3 deletion causes an autism syndrome and defects in cortical projection neurons, Nature genetics, vol.48, issue.11, pp.1359-1369, 2016.
URL : https://hal.archives-ouvertes.fr/hal-02331922

X. Caubit, M. C. Tiveron, H. Cremer, and L. Fasano, Expression patterns of the three Teashirtrelated genes define specific boundaries in the developing and postnatal mouse forebrain, The Journal of comparative neurology, vol.486, issue.1, pp.76-88, 2005.
URL : https://hal.archives-ouvertes.fr/hal-00118510

B. A. Cerny and H. F. Kaiser, A Study Of A Measure Of Sampling Adequacy For Factor-Analytic Correlation Matrices, Multivariate behavioral research, vol.12, issue.1, pp.43-47, 1977.

D. Chabbert, X. Caubit, P. L. Roubertoux, M. Carlier, B. Habermann et al.,

L. Fasano and P. Gubellini, Postnatal Tshz3 Deletion Drives Altered Corticostriatal Function and Autism Spectrum Disorder-like Behavior, Biological Psychiatry, vol.86, pp.274-285, 2019.
URL : https://hal.archives-ouvertes.fr/hal-02323149

J. Cohen, Statistical power analysis for the behavioral sciences (2 nd Ed). Lawrence Earlbaum Associates, 1988.

C. Cohen-salmon, M. Carlier, P. Roubertoux, J. Jouhaneau, C. Semal et al., Differences in patterns of pup care in mice. V--Pup ultrasonic emissions and pup care behavior, Physiology & behavior, vol.35, issue.2, pp.167-174, 1985.

M. L. Cuccaro, Y. Shao, J. Grubber, M. Slifer, C. M. Wolpert et al., Factor analysis of restricted and repetitive behaviors in autism using the Autism Diagnostic Interview-R, Child psychiatry and human development, vol.34, issue.1, pp.3-17, 2003.

D. Eilam, R. Zor, H. Szechtman, and H. Hermesh, Rituals, stereotypy and compulsive behavior in animals and humans, Neuroscience and biobehavioral reviews, vol.30, issue.4, pp.456-471, 2006.

I. Ercan, D. Sigirli, and G. Ozkaya, Examining the variations in the results of the Hotelling T(2) test in case of changing baseline landmarks in the Bookstein coordinates. Interdisciplinary sciences, computational life sciences, 2015.

R. L. Francis, The Preyer reflex audiogram of several rodents, and its relation to the "absolute" audiogram in the rat, The Journal of auditory research, vol.19, issue.3, pp.217-233, 1979.

T. W. Frazier, E. A. Youngstrom, C. S. Kubu, L. Sinclair, and A. Rezai, Exploratory and confirmatory factor analysis of the autism diagnostic interview-revised, Journal of autism and developmental disorders, vol.38, issue.3, pp.474-480, 2008.

S. Georgiades, P. Szatmari, L. Zwaigenbaum, E. Duku, S. Bryson et al., Structure of the autism symptom phenotype: A proposed multidimensional model, Journal of the American Academy of Child and Adolescent Psychiatry, vol.46, issue.2, pp.188-196, 2007.

E. Gessaroli, E. Santelli, G. Di-pellegrino, and F. Frassinetti, Personal space regulation in childhood autism spectrum disorders, PloS one, vol.8, issue.9, p.74959, 2013.

C. M. Gillan, M. Papmeyer, S. Morein-zamir, B. J. Sahakian, N. A. Fineberg et al., Disruption in the balance between goal-directed behavior and habit learning in obsessive-compulsive disorder, The American journal of psychiatry, vol.168, issue.7, pp.718-726, 2011.

B. E. Ginsburg and W. C. Allee, Some effects on conditioning on social dominance and subordination in inbred strains of mice, Physiology and Zoology, pp.15485-506, 1942.

R. L. Goldin, J. L. Matson, K. Tureck, P. E. Cervantes, and J. Jang, A comparison of tantrum behavior profiles in children with ASD, ADHD and comorbid ASD and ADHD, Research in developmental disabilities, vol.34, issue.9, pp.2669-2675, 2013.

A. M. Graybiel and S. L. Rauch, Toward a neurobiology of obsessive-compulsive disorder, Neuron, vol.28, issue.2, pp.343-347, 2000.

R. Grove, I. Roth, and R. A. Hoekstra, The motivation for special interests in individuals with autism and controls: Development and validation of the special interest motivation scale, Autism research : official journal of the International Society for Autism Research, vol.9, issue.6, pp.677-688, 2016.

E. Hashemi, P. Sahbaie, M. F. Davies, J. D. Clark, and T. M. Delorey, Gabrb3 gene deficient mice exhibit increased risk assessment behavior, hypotonia and expansion of the plexus of locus coeruleus dendrites, Brain research, vol.1129, issue.1, pp.191-199, 2007.

J. Horder, T. Lavender, M. A. Mendez, R. O'gorman, E. Daly et al., Reduced subcortical glutamate/glutamine in adults with autism spectrum disorders: a [(1)H]MRS study, Translational psychiatry, pp.3-279, 2013.

F. Irie, H. Badie-mahdavi, and Y. Yamaguchi, Autism-like socio-communicative deficits and stereotypies in mice lacking heparan sulfate, Proceedings of the National Academy of Sciences of the United States of America, vol.109, issue.13, pp.5052-5056, 2012.

R. Kawa and E. Pisula, Locomotor activity, object exploration and space preference in children with autism and Down syndrome, Acta neurobiologiae experimentalis, vol.70, issue.2, pp.131-140, 2010.

T. M. Kazdoba, P. T. Leach, M. Yang, J. L. Silverman, M. Solomon et al., Translational Mouse Models of Autism: Advancing Toward Pharmacological Therapeutics, 2015.

A. Khanegheini, M. Nasehi, and M. R. Zarrindast, The modulatory effect of CA1 GABAb receptors on ketamine-induced spatial and non-spatial novelty detection deficits with respect to Ca(2+), Neuroscience, vol.305157, p.168, 2015.

M. C. Lai, M. V. Lombardo, and S. Baron-cohen, Autism. Lancet, vol.383, issue.9920, pp.896-910, 2014.

C. Lever, S. Burton, and J. O'keefe, Rearing on hind legs, environmental novelty, and the hippocampal formation, Reviews in the neurosciences, vol.17, issue.1-2, pp.111-133, 2006.

N. Lévy and P. L. Roubertoux, Organism model: choosing the good model. In: Roubertoux P (ed) Organism model of autism spectrum disorders, pp.3-28, 2015.

R. A. Lundwall, K. G. Stephenson, E. S. Neeley-tass, J. C. Cox, M. South et al., Relationship between brain stem volume and aggression in children diagnosed with autism spectrum disorder, pp.3444-51, 2017.

R. Macdonald, G. Green, R. Mansfield, A. Geckeler, N. Gardenier et al., Stereotypy in young children with autism and typically developing children, Research in developmental disabilities, vol.28, issue.3, pp.266-277, 2007.

S. Mitaki, M. Isomura, K. Maniwa, M. Yamasaki, A. Nagai et al., Impact of five SNPs in dopamine-related genes on executive function, Acta neurologica Scandinavica, vol.127, issue.1, pp.70-76, 2013.

L. Mottron, S. Mineau, G. Martel, C. S. Bernier, C. Berthiaume et al., Lateral glances toward moving stimuli among young children with autism: Early regulation of locally oriented perception?, Development and psychopathology, vol.19, issue.1, pp.23-36, 2007.

S. S. Moy, J. J. Nadler, N. B. Young, R. J. Nonneman, A. W. Grossman et al., Social approach in genetically engineered mouse lines relevant to autism, Genes, brain, and behavior, vol.8, issue.2, pp.129-142, 2009.

R. C. Murray, M. C. Logan, and K. A. Horner, Striatal patch compartment lesions reduce stereotypy following repeated cocaine administration, Brain research, pp.1618286-298, 2015.

D. Muthugovindan and H. Singer, Motor stereotypy disorders, Current opinion in neurology, vol.22, issue.2, pp.131-136, 2009.

J. J. Nadler, S. S. Moy, G. Dold, D. Trang, N. Simmons et al., Automated apparatus for quantitation of social approach behaviors in mice, Genes, brain, and behavior, vol.3, issue.5, pp.303-314, 2004.

K. Njung'e and S. L. Handley, Effects of 5-HT uptake inhibitors, agonists and antagonists on the burying of harmless objects by mice; a putative test for anxiolytic agents, British journal of pharmacology, vol.104, issue.1, pp.105-112, 1991.

B. L. Pearson, E. B. Defensor, D. C. Blanchard, and R. J. Blanchard, C57BL/6J mice fail to exhibit preference for social novelty in the three-chamber apparatus, Behavioural brain research, vol.213, issue.2, pp.189-194, 2010.

Z. Peter, M. E. Oliphant, and T. V. Fernandez, Motor Stereotypies: A Pathophysiological Review, p.11171, 2017.

C. V. Portfors and D. J. Perkel, The role of ultrasonic vocalizations in mouse communication, Current opinion in neurobiology, pp.28115-120, 2014.

M. F. Presti, C. J. Watson, R. T. Kennedy, M. Yang, and M. H. Lewis, Behavior-related alterations of striatal neurochemistry in a mouse model of stereotyped movement disorder, Pharmacology, biochemistry, and behavior, vol.77, issue.3, pp.501-507, 2004.

G. Raux, E. Bumsel, B. Hecketsweiler, T. Van-amelsvoort, J. Zinkstok et al., Involvement of hyperprolinemia in cognitive and psychiatric features of the 22q11 deletion syndrome, Human molecular genetics, vol.16, issue.1, pp.83-91, 2007.
URL : https://hal.archives-ouvertes.fr/hal-01440622

J. Richler, S. L. Bishop, J. R. Kleinke, and C. Lord, Restricted and repetitive behaviors in young children with autism spectrum disorders, Journal of autism and developmental disorders, vol.37, issue.1, pp.73-85, 2007.

S. J. Rizzo, Repetitive Behavioral Assessments for Compound Screening in Mouse Models of Autism Spectrum Disorders, 2016.

P. Roubertoux, M. Carlier, and S. Tordjman, Deficit in Social Relationships and Reduced Field of Interest in Mice, Roubertoux PL (ed) organism Models of Autism Spectrum Disorder, pp.335-70, 2015.

P. L. Roubertoux, Maintaining Mice for Neurobehavioral Examination. In: Roubertoux PL (ed) organism models of autism spectrum disorders, pp.319-333, 2015.

P. L. Roubertoux, N. Baril, P. Cau, C. Scajola, A. Ghata et al., Differential Brain, Cognitive and Motor Profiles Associated with Partial Trisomy. Modeling Down Syndrome in Mice, Behavior genetics, vol.47, issue.3, pp.305-322, 2017.
URL : https://hal.archives-ouvertes.fr/hal-01614900

P. L. Roubertoux, B. Martin, L. Roy, I. Beau, J. Marchaland et al., Vocalizations in newborn mice: genetic analysis, Behavior genetics, vol.26, issue.4, pp.427-437, 1996.

P. L. Roubertoux and S. Tordjman, The autistic spectrum disorders (ASD): from the clinics to the molecular analysis. In: Roubertoux PL (ed) Organism models of Autism Spectrum Disorders, pp.29-66, 2015.

L. Scahill, A. Dimitropoulos, C. J. Mcdougle, M. G. Aman, I. D. Feurer et al., , 2014.

, Children's Yale-Brown obsessive compulsive scale in autism spectrum disorder: component structure and correlates of symptom checklist, Journal of the American Academy of Child and Adolescent Psychiatry, vol.53, issue.1, p.101

J. Shuster, A. Perry, J. Bebko, and M. E. Toplak, Review of factor analytic studies examining symptoms of autism spectrum disorders, Journal of autism and developmental disorders, vol.44, issue.1, pp.90-110, 2014.

J. L. Silverman, D. G. Smith, S. J. Rizzo, M. N. Karras, S. M. Turner et al., Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism, Science translational medicine, vol.4, issue.131, pp.131-151, 2012.

J. L. Silverman, M. Yang, C. Lord, and J. N. Crawley, Behavioural phenotyping assays for mouse models of autism, Nature reviews Neuroscience, vol.11, issue.7, pp.490-502, 2010.

C. J. Smith, C. M. Lang, L. Kryzak, A. Reichenberg, E. Hollander et al., Familial associations of intense preoccupations, an empirical factor of the restricted, repetitive behaviors and interests domain of autism, vol.50, pp.982-990, 2009.

E. M. Sorensen, F. Bertelsen, P. Weikop, M. M. Skovborg, T. Banke et al., Hyperactivity and lack of social discrimination in the adolescent Fmr1 knockout mouse, Behavioural pharmacology, vol.26, pp.733-740, 2015.

P. Szatmari, S. Georgiades, S. Bryson, L. Zwaigenbaum, W. Roberts et al., Investigating the structure of the restricted, repetitive behaviours and interests domain of autism, vol.47, pp.582-590, 2006.

A. Tan, M. Salgado, and S. Fahn, The characterization and outcome of stereotypical movements in nonautistic children, Movement disorders : official journal of the Movement Disorder Society, vol.12, issue.1, pp.47-52, 1997.

A. Thomas, A. Burant, N. Bui, D. Graham, L. A. Yuva-paylor et al., Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety, Psychopharmacology, vol.204, issue.2, pp.361-373, 2009.

S. Tobias and J. E. Carlson, Brief Report: Bartlett's Test of Sphericity and Chance Findings in Factor Analysis, Multivariate behavioral research, vol.4, issue.3, pp.375-377, 1969.

S. Tordjman, D. Cohen, G. M. Anderson, M. Botbol, R. Canitano et al., Reframing autism as a behavioral syndrome and not a specific mental disorder: Implications of genetic and phenotypic heterogeneity, Neuroscience and biobehavioral reviews, pp.89132-150, 2018.
URL : https://hal.archives-ouvertes.fr/hal-01812461

S. Tordjman, D. Drapier, O. Bonnot, R. Graignic, S. Fortes et al., Animal models relevant to schizophrenia and autism: validity and limitations, Behavior genetics, vol.37, issue.1, pp.61-78, 2007.

K. Tureck, J. L. Matson, A. May, and N. Turygin, Externalizing and tantrum behaviours in children with ASD and ADHD compared to children with ADHD, Developmental neurorehabilitation, vol.16, issue.1, pp.52-57, 2013.

L. M. Turner-brown, K. S. Lam, T. N. Holtzclaw, G. S. Dichter, and J. W. Bodfish, Phenomenology and measurement of circumscribed interests in autism spectrum disorders, Autism : the international journal of research and practice, vol.15, issue.4, pp.437-456, 2011.

M. Uljarevic, B. Arnott, S. J. Carrington, E. Meins, C. Fernyhough et al., Development of restricted and repetitive behaviors from 15 to 77 months: Stability of two distinct subtypes?, Developmental psychology, vol.53, issue.10, pp.1859-1868, 2017.

N. D. Van-lang, A. Boomsma, S. Sytema, A. A. De-bildt, D. W. Kraijer et al., Structural equation analysis of a hypothesised symptom model in the autism spectrum, vol.47, pp.37-44, 2006.

V. Warrier, R. Toro, B. Chakrabarti, P. Bag, A. D. Borglum et al., Genome-wide analyses of self-reported empathy: correlations with autism, schizophrenia, and anorexia nervosa, Translational psychiatry, vol.8, issue.1, p.35, 2018.
URL : https://hal.archives-ouvertes.fr/pasteur-01967229

R. L. Wasserstein, N. A. Lazar, and N. A. , The ASA's Statement on p-Values: Context, Process, and Purpose, The American Statistician, vol.70, issue.2, pp.129-133, 2016.

J. M. Welch, J. Lu, R. M. Rodriguiz, N. C. Trotta, J. Peca et al., Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice, Nature, vol.448, issue.7156, pp.894-900, 2007.

W. Wolmarans, D. J. Stein, and B. H. Harvey, A psycho-behavioral perspective on modelling obsessive-compulsive disorder (OCD) in animals: The role of context, Current medicinal chemistry, 2017.

R. Yadav, S. C. Gupta, B. G. Hillman, J. M. Bhatt, D. J. Stairs et al., Deletion of glutamate delta-1 receptor in mouse leads to aberrant emotional and social behaviors, PloS one, vol.7, issue.3, p.32969, 2012.

M. Yang and J. N. Crawley, Simple behavioral assessment of mouse olfaction, Current protocols in neuroscience Chapter, vol.8, p.24, 2009.

X. Yu, A. Taylor, J. Nagai, P. Golshani, C. J. Evans et al., , 2018.

, Astrocyte Calcium Signaling In Vivo Alters Striatal Microcircuits and Causes Repetitive Behavior, Neuron, vol.99, issue.6, p.1179

L. Zuo, Y. Tan, X. Zhang, X. Wang, J. Krystal et al., New Genomewide Association Meta-Analysis of Alcohol Dependence. Alcoholism, clinical and experimental research, vol.39, issue.8, pp.1388-1395, 2015.