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Antibioprophylaxie en chirurgie et médecine interventionnelle (patients adultes). Actualisation 2017

Abstract : Infection is a risk for any intervention. In surgery, for example, pathogenic bacteria are found in more than 90% of operative wounds during closure. This exists whatever the surgical technique and whatever the environment (the laminar flow does not entirely eliminate this risk). These bacteria are few in number but can proliferate. They find in the operative wound a favourable environment (haematoma, ischaemia, modification of oxido-reduction potential…) and the intervention induces anomalies of the immune defences. In the case of the installation of foreign material, the risk is increased. The objective of antibiotic prophylaxis (ABP) is to prevent bacterial growth in order to reduce the risk of infection at the site of the intervention. The preoperative consultation represents a privileged moment to decide on the prescription of an ABP. It is possible to define the type of intervention planned, the associated risk of infection (and therefore the necessity or not of ABP), the time of prescription before surgery and any allergic antecedents which may modify the choice of the selected antibiotic molecule.
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Submitted on : Tuesday, January 21, 2020 - 3:06:22 PM
Last modification on : Wednesday, August 19, 2020 - 12:08:23 PM

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Claude Martin, Christian Auboyer, Matthieu Boisson, Hervé Dupont, Rémy Gauzit, et al.. Antibioprophylaxie en chirurgie et médecine interventionnelle (patients adultes). Actualisation 2017. Anesthésie & Réanimation, Elsevier Masson, 2019, 5 (6), pp.544-566. ⟨10.1016/j.anrea.2019.06.002⟩. ⟨hal-02447282⟩

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