A. Derghal, M. Djelloul, J. Trouslard, and L. Mounien, The role of microRNA in the modulation of the melanocortinergic system, Front. Neurosci, vol.11, p.181, 2017.
URL : https://hal.archives-ouvertes.fr/hal-01762644

G. J. Morton, D. E. Cummings, D. G. Baskin, G. S. Barsh, and M. W. Schwartz, Central nervous system control of food intake and body weight, Nature, vol.443, pp.289-295, 2006.

R. D. Cone, Anatomy and regulation of the central melanocortin system, Nat. Neurosci, vol.8, pp.571-578, 2005.

M. Schneeberger, R. Gomis, and M. Claret, Hypothalamic and brainstem neuronal circuits controlling homeostatic energy balance, J. Endocrinol, vol.220, pp.25-46, 2014.

Y. Zhang, Positional cloning of the mouse obese gene and its human homologue, Nature, vol.372, pp.425-432, 1994.

N. Balthasar, R. Coppari, J. Mcminn, S. M. Liu, C. E. Lee et al., Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis, Neuron, vol.42, pp.983-991, 2004.

L. A. Tartaglia, Identification and expression cloning of a leptin receptor, OB-R. Cell, vol.83, pp.1263-1271, 1995.

A. W. Xu, L. Ste-marie, C. B. Kaelin, and G. S. Barsh, Inactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (POMC) neurons causes decreased POMC expression, mild obesity, and defects in compensatory refeeding, Endocrinology, vol.148, pp.72-80, 2007.

C. Vaisse, J. L. Halaas, C. M. Horvath, J. E. Darnell, M. Stoffel et al., Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice, Nat. Genet, vol.14, pp.95-97, 1996.

M. G. Myers, M. A. Cowley, and H. Münzberg, Mechanisms of leptin action and leptin resistance, Annu. Rev. Physiol, vol.70, pp.537-556, 2008.

K. Rahmouni, C. D. Sigmund, W. G. Haynes, and A. L. Mark, Hypothalamic ERK mediates the anorectic and thermogenic sympathetic effects of leptin, Diabetes, vol.58, pp.536-542, 2009.

K. Iskandar, Y. Cao, Y. Hayashi, M. Nakata, E. Takano et al., PDK-1/FoxO1 pathway in POMC neurons regulates POMC expression and food intake, Am. J. Physiol. Endocrinol. Metab, vol.298, 2010.

A. Derghal, M. Djelloul, C. Airault, C. Pierre, M. Dallaporta et al., Leptin is required for hypothalamic regulation of miRNAs targeting POMC 3 UTR. Front, Cell Neurosci, vol.9, p.172, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01212345

A. Derghal, M. Djelloul, M. Azzarelli, S. Degonon, F. Tourniaire et al., MicroRNAs are involved in the hypothalamic leptin sensitivity, Epigenetics, vol.13, pp.1127-1140, 2018.
URL : https://hal.archives-ouvertes.fr/hal-02010517

M. Schneeberger, J. Altirriba, A. García, Y. Esteban, C. Castaño et al., Deletion of miRNA processing enzyme Dicer in POMC-expressing cells leads to pituitary dysfunction, neurodegeneration and development of obesity, Mol. Metab, vol.2, pp.74-85, 2012.

Y. Greenman, Y. Kuperman, Y. Drori, S. L. Asa, I. Navon et al., Postnatal ablation of POMC neurons induces an obese phenotype characterized by decreased food intake and enhanced anxiety-like behavior, Mol. Endocrinol, vol.27, pp.1091-1102, 2013.

S. Croizier, S. Park, J. Maillard, and S. G. Bouret, Central Dicer-miR-103/107 controls developmental switch of POMC progenitors into NPY neurons and impacts glucose homeostasis
URL : https://hal.archives-ouvertes.fr/hal-02375382

A. Derghal, M. Djelloul, J. Trouslard, and L. Mounien, An Emerging role of micro-RNA in the effect of the endocrine disruptors, Front. Neurosci, vol.10, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01471933

D. P. Bartel, MicroRNAs: Genomics, biogenesis, mechanism, and function, Cell, vol.116, pp.281-297, 2004.

, J. Clin. Med, vol.8, p.2213, 2019.

D. Baek, J. Villén, C. Shin, F. D. Camargo, S. P. Gygi et al., The impact of microRNAs on protein output, Nature, vol.455, pp.64-71, 2008.

D. P. Bartel and . Micrornas, Target recognition and regulatory functions, vol.136, pp.215-233, 2009.

J. Landrier, A. Derghal, and L. Mounien, MicroRNAs in obesity and related metabolic disorders, vol.8, p.859, 2019.
URL : https://hal.archives-ouvertes.fr/hal-02487569

W. Gu, Y. Xu, X. Xie, T. Wang, J. Ko et al., The role of RNA structure at 5 untranslated region in microRNA-mediated gene regulation, RNA, vol.20, pp.1369-1375, 2014.

I. Lee, S. S. Ajay, J. I. Yook, H. S. Kim, S. H. Hong et al., New class of microRNA targets containing simultaneous 5 -UTR and 3 -UTR interaction sites

, Genome Res, vol.19, pp.1175-1183, 2009.

J. J. Forman and H. A. Coller, The code within the code: microRNAs target coding regions, Cell Cycle, vol.9, pp.1533-1541, 2010.

H. Guo, N. T. Ingolia, J. S. Weissman, and D. P. Bartel, Mammalian microRNAs predominantly act to decrease target mRNA levels, Nature, vol.466, pp.835-840, 2010.

J. Wang, M. Lu, C. Qiu, and Q. Cui, TransmiR: A transcription factor-microRNA regulation database, Nucleic Acids Res, vol.38, pp.119-122, 2010.

Z. Li, L. Ji, S. Su, X. Zhu, F. Cheng et al., Leptin up-regulates microRNA-27a/b-3p level in hepatic stellate cells, Exp. Cell Res, vol.366, pp.63-70, 2018.

A. Nazarians-armavil, J. A. Chalmers, C. B. Lee, W. Ye, and D. D. Belsham, Cellular insulin resistance disrupts hypothalamic mHypoA-POMC/GFP neuronal signaling pathways, J. Endocrinol, vol.220, pp.13-24, 2014.

I. S. Vlachos, K. Zagganas, M. D. Paraskevopoulou, G. Georgakilas, D. Karagkouni et al., DIANA-miRPath v3.0: Deciphering microRNA function with experimental support, Nucleic Acids Res, vol.43, pp.460-466, 2015.

M. Muiños-gimeno, Y. Espinosa-parrilla, M. Guidi, B. Kagerbauer, T. Sipilä et al., Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 are associated with panic disorder and regulate several anxiety candidate genes and related pathways, Biol. Psychiatry, vol.69, pp.526-533, 2011.

H. Wang, S. Ma, L. Xue, Y. Li, J. Wang et al., MiR-488 determines coat pigmentation by down-regulating the pigment-producing gene pro-opiomelanocortin, Cell. Mol. Biol, vol.62, pp.37-43, 2016.

L. Mounien, N. Marty, D. Tarussio, S. Metref, D. Genoux et al., Glut2-dependent glucose-sensing controls thermoregulation by enhancing the leptin sensitivity of NPY and POMC neurons, FASEB J, vol.24, pp.1747-1758, 2010.

L. Mounien, J. Do-rego, P. Bizet, I. Boutelet, G. Gourcerol et al., Pituitary adenylate cyclase-activating polypeptide inhibits food intake in mice through activation of the hypothalamic melanocortin system, Neuropsychopharmacology, vol.34, pp.424-435, 2009.
URL : https://hal.archives-ouvertes.fr/inserm-00349463

C. Toda, A. Santoro, J. D. Kim, S. Diano, and . Neurons, From birth to death, Annu. Rev. Physiol, vol.79, pp.209-236, 2017.

S. M. Sternson, D. Atasoy, J. N. Betley, F. E. Henry, and S. Xu, An emerging technology framework for the neurobiology of appetite, Cell Metab, vol.23, pp.234-253, 2016.

M. Koch, L. Varela, J. G. Kim, J. D. Kim, F. Hernández-nuño et al., Hypothalamic POMC neurons promote cannabinoid-induced feeding, Nature, vol.519, pp.45-50, 2015.

E. K. Mcilwraith, N. Loganathan, and D. D. Belsham, Regulation of Gpr173 expression, a putative phoenixin receptor, by saturated fatty acid palmitate and endocrine-disrupting chemical bisphenol A through a p38-mediated mechanism in immortalized hypothalamic neurons, Mol. Cell. Endocrinol, vol.485, pp.54-60, 2019.

A. Salehi, N. Loganathan, and D. D. Belsham, Bisphenol A induces POMC gene expression through neuroinflammatory and PPAR? nuclear receptor-mediated mechanisms in POMC-expressing hypothalamic neuronal models, Mol. Cell. Endocrinol, vol.479, pp.12-19, 2019.

E. K. Tse and D. D. Belsham, Palmitate induces neuroinflammation, ER stress, and POMC mRNA expression in hypothalamic mHypoA-POMC/GFP neurons through novel mechanisms that are prevented by oleate, Mol. Cell. Endocrinol, vol.472, pp.40-49, 2018.

Y. Cui, L. Chen, H. Yao, J. Zhang, and K. Ding, Upregulation of microRNA-383 inhibits the proliferation, migration and invasion of colon cancer cells, Oncol. Lett, vol.15, pp.1184-1190, 2018.

B. Gu, J. Wang, Y. Song, Q. Wang, and Q. Wu, MicroRNA-383 regulates cell viability and apoptosis by mediating Wnt/?-catenin signaling pathway in non-small cell lung cancer, J. Cell. Biochem, vol.120, pp.7918-7926, 2018.

J. Lian, H. Tian, L. Liu, X. Zhang, W. Li et al., Downregulation of microRNA-383 is associated with male infertility and promotes testicular embryonal carcinoma cell proliferation by targeting IRF1

X. Wang, G. Ding, W. Lai, S. Liu, and J. Shuai, MicroRNA-383 upregulation protects against propofol-induced hippocampal neuron apoptosis and cognitive impairment, Exp. Med, vol.15, pp.3181-3188, 2018.

P. Teng, Y. Jiao, M. Hao, and X. Tang, MicroRNA-383 suppresses the PI3K-AKT-MTOR signaling pathway to inhibit development of cervical cancer via down-regulating PARP2, J. Cell. Biochem, vol.119, pp.5243-5252, 2018.

D. Cota, K. Proulx, K. A. Smith, S. C. Kozma, G. Thomas et al., Hypothalamic mTOR signaling regulates food intake, Science, vol.312, pp.927-930, 2006.

S. Yang, A. Tien, G. Boddupalli, A. W. Xu, Y. N. Jan et al., Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons, Neuron, vol.75, pp.425-436, 2012.

F. Xia, J. Sun, Y. Jiang, and C. Li, MicroRNA-384-3p inhibits retinal neovascularization through targeting hexokinase 2 in mice with diabetic retinopathy, J. Cell. Physiol, vol.234, pp.721-730, 2018.

A. Khlaifia, I. Matias, D. Cota, and F. Tell, Nutritional status-dependent endocannabinoid signalling regulates the integration of rat visceral information, J. Physiol, vol.595, pp.3267-3285, 2017.

Y. Qi and Y. Yang, Hunger states control the directions of synaptic plasticity via switching cell type-specific subunits of NMDA receptors, J. Neurosci, vol.35, pp.13171-13182, 2015.

M. Ha and V. N. Kim, Regulation of microRNA biogenesis, Nat. Rev. Mol. Cell Biol, vol.15, pp.509-524, 2014.

J. Krol, I. Loedige, and W. Filipowicz, The widespread regulation of microRNA biogenesis, function and decay, Nat. Rev. Genet, vol.11, pp.597-610, 2010.

V. N. Kim, J. Han, and M. C. Siomi, Biogenesis of small RNAs in animals, Nat. Rev. Mol. Cell Biol, vol.10, pp.126-139, 2009.

X. Liao, L. Zheng, H. He, D. Zheng, Z. Wei et al., STAT3 regulated ATR via microRNA-383 to control DNA damage to affect apoptosis in A431 cells, Cell. Signal, vol.27, pp.2285-2295, 2015.

F. Ozsolak, L. L. Poling, Z. Wang, H. Liu, X. S. Liu et al., Chromatin structure analyses identify miRNA promoters, Genes Dev, vol.22, pp.3172-3183, 2008.