, The World Health Organization (WHO), 2012.
Adipocyte turnover: Relevance to human adipose tissue morphology, Diabetes, vol.59, pp.105-109, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-00542528
Transcriptional control of adipocyte formation, Cell Metab, vol.4, pp.263-273, 2006. ,
20 years of leptin: Leptin at 20: An overview, J. Endocrinol, vol.223, pp.1-8, 2014. ,
Dietary regulation of adiponectin by direct and indirect lipid activators of nuclear hormone receptors, Mol. Nutr. Food Res, vol.60, pp.175-184, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01478689
Inflammatory mechanisms in obesity, Annu. Rev. Immunol, vol.29, pp.415-445, 2011. ,
Chemokine Expression in Inflamed Adipose Tissue Is Mainly Mediated by NF-kappaB, PLoS ONE, vol.8, 2013. ,
Obesity-associated Inflammation Induces microRNA-155 Expression in Adipocytes and Adipose Tissue: Outcome on Adipocyte Function, J. Clin. Endocrinol. Metab, vol.101, pp.1615-1626, 2016. ,
URL : https://hal.archives-ouvertes.fr/inserm-01478345
Vitamin D limits inflammation-linked microRNA expression in adipocytes in vitro and in vivo: A new mechanism for the regulation of inflammation by vitamin D, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01595263
Macrophages, inflammation, and insulin resistance, Annu. Rev. Physiol, vol.72, pp.219-246, 2010. ,
Obesity is associated with macrophage accumulation in adipose tissue, J. Clin. Investig, vol.112, pp.1796-1808, 2003. ,
Role of macrophage tissue infiltration in obesity and insulin resistance, Diabetes Metab, vol.35, pp.251-260, 2009. ,
URL : https://hal.archives-ouvertes.fr/inserm-00410101
The metabolic syndrome, Endocr. Rev, vol.29, pp.777-822, 2008. ,
Obesity-Induced Neuroinflammation: Beyond the Hypothalamus, Trends Neurosci, vol.40, pp.237-253, 2017. ,
The Role of MicroRNA in the Modulation of the Melanocortinergic System, Front. Neurosci, vol.11, p.181, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01762644
Central nervous system control of food intake and body weight, Nature, vol.443, pp.289-295, 2006. ,
Multiple neural systems controlling food intake and body weight, Neurosci. Biobehav. Rev, vol.26, pp.393-428, 2002. ,
Hypothalamic and brainstem neuronal circuits controlling homeostatic energy balance, J. Endocrinol, vol.220, pp.25-46, 2014. ,
Expression of melanocortin MC3 and MC4 receptor mRNAs by neuropeptide Y neurons in the rat arcuate nucleus, Neuroendocrinology, vol.82, pp.164-170, 2005. ,
Colors with functions: Elucidating the biochemical and molecular basis of carotenoid metabolism, Annu. Rev. Nutr, vol.30, pp.35-56, 2010. ,
Chronic ingestion of lycopene-rich tomato juice or lycopene supplements significantly increases plasma concentrations of lycopene and related tomato carotenoids in humans, Am. J. Clin. Nutr, vol.68, pp.1187-1195, 1998. ,
Associations between body mass index and the prevalence of low micronutrient levels among US adults, vol.8, p.59, 2006. ,
Impact of micronutrient deficiencies on obesity, Nutr. Rev, vol.67, pp.559-572, 2009. ,
Longitudinal associations between body mass index and serum carotenoids: The CARDIA study, Br. J. Nutr, vol.95, pp.358-365, 2006. ,
Dietary factors and low-grade inflammation in relation to overweight and obesity, Br. J. Nutr, vol.106, 2011. ,
Serum antioxidant status is associated with metabolic syndrome among U.S. adults in recent national surveys, J. Nutr, vol.141, pp.903-913, 2011. ,
Carotenoids, vitamin A, and their association with the metabolic syndrome: A systematic review and meta-analysis, Nutr. Rev, vol.77, pp.32-45, 2019. ,
Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity, Arch. Biochem. Biophys, vol.572, pp.112-125, 2015. ,
Effects of Mixed Carotenoids on Adipokines and Abdominal Adiposity in Children: A Pilot Study, J. Clin. Endocrinol. Metab, vol.102, 1983. ,
Effect of Oral Paprika Xanthophyll Intake on Abdominal Fat in Healthy Overweight Humans: A Randomized, Double-blind, Placebo-controlled Study, J. Oleo Sci, vol.67, pp.1149-1162, 2018. ,
, Obesity Research: Technical Considerations and Current Status of the Field. Nutrients, vol.11, 2019.
Beta-Carotene Reduces Body Adiposity of Mice via BCMO1, PLoS ONE, vol.6, 2011. ,
Gene expression response of mouse lung, liver and white adipose tissue to beta-carotene supplementation, knockout of Bcmo1 and sex, Mol. Nutr. Food Res, vol.55, pp.1466-1474, 2011. ,
Beta,beta-carotene decreases peroxisome proliferator receptor gamma activity and reduces lipid storage capacity of adipocytes in a beta,beta-carotene oxygenase 1-dependent manner, J. Biol. Chem, vol.285, pp.27891-27899, 2010. ,
Effects of astaxanthin in obese mice fed a high-fat diet, Biosci. Biotechnol. Biochem, vol.71, pp.893-899, 2007. ,
An intervention study in obese mice with astaxanthin, a marine carotenoid-effects on insulin signaling and pro-inflammatory cytokines, Food Funct, vol.3, pp.120-126, 2012. ,
Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin, E. Sci. Rep, vol.5, p.17192, 2015. ,
Astaxanthin inhibits inflammation and fibrosis in the liver and adipose tissue of mouse models of diet-induced obesity and nonalcoholic steatohepatitis, J. Nutr. Biochem, vol.43, pp.27-35, 2017. ,
Mechanism of visceral fat reduction in Tsumura Suzuki obese, diabetes (TSOD) mice orally administered beta-cryptoxanthin from Satsuma mandarin oranges (Citrus unshiu Marc), J. Agric. Food Chem, vol.59, pp.12342-12351, 2011. ,
Prevention and reversal of lipotoxicity-induced hepatic insulin resistance and steatohepatitis in mice by an antioxidant carotenoid, beta-cryptoxanthin, Endocrinology, vol.156, pp.987-999, 2015. ,
Nutraceutical effects of fucoxanthin for obesity and diabetes therapy: A review, J. Oleo Sci, vol.64, pp.125-132, 2015. ,
Fucoxanthin regulates adipocytokine mRNA expression in white adipose tissue of diabetic/obese KK-Ay mice, Arch. Biochem. Biophys, vol.504, pp.17-25, 2010. ,
Undaria pinnatifida and Fucoxanthin Ameliorate Lipogenesis and Markers of Both Inflammation and Cardiovascular Dysfunction in an Animal Model of Diet-Induced Obesity, Mar. Drugs, vol.14, 2016. ,
Anti-obesity effects of zeaxanthin on 3T3-L1 preadipocyte and high fat induced obese mice, Food Funct, vol.8, pp.3327-3338, 2017. ,
A novel cobiotic-based preventive approach against high-fat diet-induced adiposity, nonalcoholic fatty liver and gut derangement in mice, Int. J. Obes, vol.40, pp.487-496, 2016. ,
Lycopene and tomato powder supplementation similarly inhibit high-fat diet induced obesity, inflammatory response, and associated metabolic disorders, Mol. Nutr. Food Res, p.61, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01571909
Tomato Powder Inhibits Hepatic Steatosis and Inflammation Potentially Through Restoring SIRT1 Activity and Adiponectin Function Independent of Carotenoid Cleavage Enzymes in Mice, Mol. Nutr. Food Res, vol.62, 2018. ,
Lycopene ameliorates systemic inflammation-induced synaptic dysfunction via improving insulin resistance and mitochondrial dysfunction in the liver-brain axis, Food Funct, vol.10, pp.2125-2137, 2019. ,
Lycopene supplementation attenuates western diet-induced body weight gain through increasing the expressions of thermogenic/mitochondrial functional genes and improving insulin resistance in the adipose tissue of obese mice, J. Nutr. Biochem, vol.69, pp.63-72, 2019. ,
Vitamin A signaling and homeostasis in obesity, diabetes, and metabolic disorders, Pharmacol. Ther, 2019. ,
Carotene and vitamin A in human fat, Med. J. Aust, p.589, 1954. ,
Predictors of adipose tissue carotenoid and retinol levels in nine countries: The EURAMIC Study, Am. J. Epidemiol, vol.144, pp.968-979, 1996. ,
Carotenoids in human blood and tissues, J. Nutr, vol.119, pp.101-104, 1989. ,
Site-specific concentrations of carotenoids in adipose tissue: Relations with dietary and serum carotenoid concentrations in healthy adults, Am. J. Clin. Nutr, vol.90, pp.533-539, 2009. ,
Lipophilic micronutrients and adipose tissue biology, Nutrients, vol.4, pp.1622-1649, 2012. ,
Carotenoid and tocopherol composition of human adipose tissue, Am. J. Clin. Nutr, vol.47, pp.33-36, 1988. ,
Serum concentrations of beta-carotene and alpha-tocopherol are associated with diet, smoking, and general and central adiposity, Am. J. Clin. Nutr, vol.73, pp.777-785, 2001. ,
Changes in macular pigment optical density and serum concentrations of lutein and zeaxanthin in response to weight loss, Br. J. Nutr, vol.105, pp.1036-1046, 2011. ,
The concentration of beta-carotene in human adipocytes, but not the whole-body adipocyte stores, is reduced in obesity, PLoS ONE, vol.9, 2014. ,
Effects of physicochemical properties of carotenoids on their bioaccessibility, intestinal cell uptake, and blood and tissue concentrations, Mol. Nutr. Food Res, vol.56, pp.1385-1397, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-01330165
CD36 is involved in lycopene and lutein uptake by adipocytes and adipose tissue cultures, Mol. Nutr. Food Res, vol.55, pp.578-584, 2011. ,
URL : https://hal.archives-ouvertes.fr/inserm-01478649
Purified low-density lipoprotein and bovine serum albumin efficiency to internalise lycopene into adipocytes, Food Chem. Toxicol, vol.46, pp.3832-3836, 2008. ,
Relations between antioxidant vitamins in adipose tissue, plasma, and diet, Am. J. Epidemiol, vol.141, pp.440-450, 1995. ,
Relation between beta-carotene intake and plasma and adipose tissue concentrations of carotenoids and retinoids, Am. J. Clin. Nutr, vol.62, pp.598-603, 1995. ,
Relation among serum and tissue concentrations of lutein and zeaxanthin and macular pigment density, Am. J. Clin. Nutr, vol.71, pp.1555-1562, 2000. ,
Lycopene in serum, skin and adipose tissues after tomato-oleoresin supplementation in patients undergoing haemorrhoidectomy or peri-anal fistulotomy, Br. J. Nutr, vol.90, pp.759-766, 2003. ,
Individual carotenoid concentrations in adipose tissue and plasma as biomarkers of dietary intake, Am. J. Clin. Nutr, vol.76, pp.172-179, 2002. ,
Macular pigment density in relation to serum and adipose tissue concentrations of lutein and serum concentrations of zeaxanthin, Am. J. Clin. Nutr, vol.76, pp.595-603, 2002. ,
Differences between plasma and adipose tissue biomarkers of carotenoids and tocopherols, Cancer Epidemiol. Prev. Biomark, vol.7, pp.1043-1048, 1998. ,
Plasma carotenoid concentrations are inversely correlated with fat mass in older women, J. Nutr. Health Aging, vol.2, pp.79-83, 1998. ,
CMO1 deficiency abolishes vitamin A production from beta-carotene and alters lipid metabolism in mice, J. Biol. Chem, vol.282, pp.33553-33561, 2007. ,
beta-Carotene conversion products and their effects on adipose tissue, Genes Nutr, vol.4, pp.179-187, 2009. ,
Retinaldehyde represses adipogenesis and diet-induced obesity, Nat. Med, vol.13, pp.695-702, 2007. ,
Retinoids and retinoid-binding protein expression in rat adipocytes, J. Biol. Chem, vol.267, pp.1805-1810, 1992. ,
Analysis, occurrence, and function of 9-cis-retinoic acid, Biochim. Biophys. Acta, vol.1821, pp.10-20, 2012. ,
Retinoids and retinoid-metabolic gene expression in mouse adipose tissues, Biochem. Cell Biol, vol.89, pp.578-584, 2011. ,
Retinoid absorption and storage is impaired in mice lacking lecithin ,
, J. Biol. Chem, vol.280, pp.35647-35657, 2005.
Reduced adiponectin expression after high-fat diet is associated with selective up-regulation of ALDH1A1 and further retinoic acid receptor signaling in adipose tissue, vol.31, pp.203-211, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01595261
International Union of Pharmacology. LXIII. Retinoid X receptors, Pharmacol. Rev, vol.58, pp.760-772, 2006. ,
URL : https://hal.archives-ouvertes.fr/hal-00187925
International Union of Pharmacology. LX. Retinoic acid receptors, Pharmacol. Rev, vol.58, pp.712-725, 2006. ,
URL : https://hal.archives-ouvertes.fr/hal-00187925
The contribution of vitamin A to autocrine regulation of fat depots, Biochim. Biophys. Acta, vol.1821, pp.190-197, 2012. ,
All-trans-retinoic acid represses obesity and insulin resistance by activating both peroxisome proliferation-activated receptor beta/delta and retinoic acid receptor, Mol. Cell. Biol, vol.29, pp.3286-3296, 2009. ,
Lycopene induces retinoic acid receptor transcriptional activation in mice, Mol. Nutr. Food Res, vol.56, pp.702-712, 2012. ,
Apo-10 -lycopenoic acid impacts adipose tissue biology via the retinoic acid receptors, Biochim. Biophys. Acta, vol.1811, pp.1105-1114, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-01330314
, Adv. Food Nutr. Res, vol.51, pp.99-164, 2006.
Carotenoids and apocarotenoids in cellular signaling related to cancer: A review, Mol. Nutr. Food Res, vol.56, pp.259-269, 2012. ,
Carotenoids activate the antioxidant response element transcription system, Mol. Cancer Ther, vol.4, pp.177-186, 2005. ,
, Les Phytomicronutriments, 2012.
Carotenoids and retinoids as suppressors on adipocyte differentiation via nuclear receptors, Biofactors, vol.13, pp.103-109, 2000. ,
Asymmetric cleavage of beta-carotene yields a transcriptional repressor of retinoid X receptor and peroxisome proliferator-activated receptor responses, Mol. Endocrinol, vol.21, pp.77-88, 2007. ,
?-Cryptoxanthin suppresses the adipogenesis of 3T3-L1 cells via RAR activation, J. Nutr. Sci. Vitaminol, vol.57, pp.426-431, 2011. ,
Astaxanthin functions differently as a selective peroxisome proliferator-activated receptor gamma modulator in adipocytes and macrophages, Biochem. Pharmacol, vol.84, pp.692-700, 2012. ,
Fucoxanthin and its metabolite, fucoxanthinol, suppress adipocyte differentiation in 3T3-L1 cells, Int. J. Mol. Med, vol.18, pp.147-152, 2006. ,
Fucoxanthin Suppresses Lipid Accumulation and ROS Production During Differentiation in 3T3-L1 Adipocytes, Phytother. Res, vol.30, pp.1802-1808, 2016. ,
Goda, T. ?-Carotene accumulation in 3T3-L1 adipocytes inhibits the elevation of reactive oxygen species and the suppression of genes related to insulin sensitivity induced by tumor necrosis factor-alpha, Nutrition, vol.26, pp.1151-1156, 2010. ,
?-Carotene Inhibits Activation of NF-kappaB, Activator Protein-1, and STAT3 and Regulates Abnormal Expression of Some Adipokines in 3T3-L1 Adipocytes, J. Cancer Prev, vol.23, pp.37-43, 2018. ,
Metabolite of Fucoxanthin, Improves Obesity-Induced Inflammation in Adipocyte Cells, Mar. Drugs, vol.13, pp.4799-4813, 2015. ,
Lycopene inhibits proinflammatory cytokine and chemokine expression in adipose tissue, J. Nutr. Biochem, vol.22, pp.642-648, 2011. ,
URL : https://hal.archives-ouvertes.fr/inserm-01478678
Lycopene attenuates LPS-induced TNF-alpha secretion in macrophages and inflammatory markers in adipocytes exposed to macrophage-conditioned media, Mol. Nutr. Food Res, vol.56, pp.725-732, 2012. ,
all-E)-and (5Z)-Lycopene Display Similar Biological Effects on Adipocytes, Mol. Nutr. Food Res, vol.63, 2019. ,
URL : https://hal.archives-ouvertes.fr/hal-01998506
Adipsin gene expression in 3T3-F442A adipocytes is posttranscriptionally down-regulated by retinoic acid, J. Biol. Chem, vol.266, pp.1157-1161, 1991. ,
Modulation of resistin expression by retinoic acid and vitamin A status, Diabetes, vol.53, pp.882-889, 2004. ,
All-trans-retinoic acid represses chemokine expression in adipocytes and adipose tissue by inhibiting NF-kappaB signaling, J. Nutr. Biochem, vol.42, pp.101-107, 2017. ,
Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans, Diabetes, vol.63, pp.4089-4099, 2014. ,
Zeaxanthin promotes mitochondrial biogenesis and adipocyte browning via AMPKalpha1 activation, Food Funct, vol.10, pp.2221-2233, 2019. ,
All-trans retinoic acid induces oxidative phosphorylation and mitochondria biogenesis in adipocytes, J. Lipid Res, vol.56, pp.1100-1109, 2016. ,
Fucoxanthin and Its Metabolite Fucoxanthinol Do Not Induce Browning in Human Adipocytes, J. Agric. Food Chem, vol.65, pp.10915-10924, 2017. ,
Modulation of leptin resistance by food compounds, Mol. Nutr. Food Res, vol.60, pp.1789-1803, 2016. ,
Carotenoid, tocopherol, and retinol concentrations in elderly human brain, J. Nutr. Health Aging, vol.8, pp.156-162, 2004. ,
Relationship between Serum and Brain Carotenoids, alpha-Tocopherol, and Retinol Concentrations and Cognitive Performance in the Oldest Old from the Georgia Centenarian Study, J. Aging Res, 2013. ,
Study on the expression of c-Fos protein in the brain of rats after ingestion of food rich in lycopene, Neurosci. Lett, vol.536, pp.1-5, 2013. ,
Lycopene attenuates diabetes-associated cognitive decline in rats, Life Sci, vol.83, pp.128-134, 2008. ,
Anti-Neuroinflammatory Effects of Fucoxanthin via Inhibition of Akt/NF-kappaB and MAPKs/AP-1 Pathways and Activation of PKA/CREB Pathway in Lipopolysaccharide-Activated BV-2 Microglial Cells, Neurochem. Res, vol.42, pp.667-677, 2017. ,
Fucoxanthin prevents lipopolysaccharide-induced depressive-like behavior in mice via AMPK-NF-kappaB pathway, Metab. Brain Dis, vol.34, pp.431-442, 2019. ,
AMP-activated protein kinase: Maintaining energy homeostasis at the cellular and whole-body levels, Annu. Rev. Nutr, vol.34, pp.31-55, 2014. ,