The aryl hydrocarbon receptor-activating effect of uremic toxins from tryptophan metabolism: A new concept to understand cardiovascular complications of chronic kidney disease, Toxins (Basel), vol.6, pp.934-949, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-01610428
Activation of the Ah receptor by tryptophan and tryptophan metabolites, Biochemistry, vol.37, pp.11508-11515, 1998. ,
The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor, Biochemistry, vol.49, pp.393-400, 2010. ,
Tryptophan-Derived Uremic Toxins and Thrombosis in Chronic Kidney Disease, Toxins (Basel, vol.10, p.412, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-02068080
Aryl hydrocarbon receptor is activated in patients and mice with chronic kidney disease, Kidney Int, vol.93, pp.986-999, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-02060310
AhR signaling pathways and regulatory functions, Biochim. Open, vol.7, pp.1-9, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-02196328
Molecular mechanisms of AhR functions in the regulation of cytochrome P450 genes, Biochem. Biophys. Res. Commun, vol.338, pp.311-317, 2005. ,
Regulation of constitutive and inducible AHR signaling: Complex interactions involving the AHR repressor, Biochem. Pharmacol, vol.77, pp.485-497, 2009. ,
TCDD-induced cyclooxygenase-2 expression is mediated by the nongenomic pathway in mouse MMDD1 macula densa cells and kidneys, Biochem. Pharmacol, vol.79, pp.487-497, 2010. ,
Cyclooxygenase-2 promoter activation by the aromatic hydrocarbon receptor in breast cancer mcf-7 cells: repressive effects of conjugated linoleic acid, Nutr. Cancer, vol.59, pp.248-257, 2007. ,
The cardiovascular effect of the uremic solute indole-3 acetic acid, J. Am. Soc. Nephrol, vol.26, pp.876-887, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01610425
Indolic uremic solutes increase tissue factor production in endothelial cells by the aryl hydrocarbon receptor pathway, Kidney Int, vol.84, pp.733-744, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-01610430
Mechanisms of tissue factor induction by the uremic toxin indole-3 acetic acid through aryl hydrocarbon receptor/nuclear factor-kappa B signaling pathway in human endothelial cells, Arch. Toxicol, vol.93, pp.121-136, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-02060898
Expression of CYP1A1 and CYP1B1 in human endothelial cells: regulation by fluid shear stress, Cardiovasc. Res, vol.81, pp.669-677, 2009. ,
Aryl hydrocarbon receptor mediates laminar fluid shear stress-induced CYP1A1 activation and cell cycle arrest in vascular endothelial cells, Cardiovasc. Res, vol.77, pp.809-818, 2008. ,
Go with the flow": how Kruppel-like factor 2 regulates the vasoprotective effects of shear stress, Antioxid. Redox Signal, vol.15, pp.1449-1461, 2011. ,
Human AHR functions in vascular tissue: Pro-and anti-inflammatory responses of AHR agonists in atherosclerosis, Biochem. Pharmacol, vol.159, pp.116-120, 2019. ,
The inhibitory mechanisms of the tyrosine kinase inhibitors herbimycin a, genistein, and tyrphostin B48 with regard to the function of the aryl hydrocarbon receptor in Caco-2 cells, Biosci. Biotechnol. Biochem, vol.74, pp.36-43, 2010. ,
, Int. J. Mol. Sci, vol.2020, p.2392
DNA microarray reveals changes in gene expression of shear stressed human umbilical vein endothelial cells, Proc. Natl. Acad. Sci, vol.98, pp.8955-8960, 2001. ,
Endothelial cell cytochrome P450 1A1 and 1B1: up-regulation by shear stress, vol.11, pp.1-10, 2004. ,
Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context, Environ. Health Perspect, vol.111, pp.1877-1882, 2003. ,
The aryl hydrocarbon receptor is activated by modified low-density lipoprotein, Proc. Natl. Acad. Sci, vol.104, pp.1412-1417, 2007. ,
CH223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor, Toxicol. Sci, vol.117, pp.393-403, 2010. ,
The Aryl Hydrocarbon Receptor is a Critical Regulator of Tissue Factor Stability and an Antithrombotic Target in Uremia, J. Am. Soc. Nephrol, vol.27, pp.189-201, 2016. ,
Tissue factor at the crossroad of coagulation and cell signaling, J. Thromb. Haemost, vol.16, pp.1941-1952, 2018. ,
Allosteric disulfide bonds in thrombosis and thrombolysis, J. Thromb. Haemost, vol.4, pp.2533-2541, 2006. ,
Shear stress-initiated signaling and its regulation of endothelial function, Arterioscler. Thromb. Vasc. Biol, vol.34, pp.2191-2198, 2014. ,
The uremic solute indoxyl sulfate induces oxidative stress in endothelial cells, J. Thromb. Haemost, vol.5, pp.1302-1308, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-01610441
Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria, J. Clin. Invest, vol.52, pp.2745-2756, 1973. ,
Review on uremic toxins: classification, concentration, and interindividual variability, Kidney Int, vol.63, pp.1934-1943, 2003. ,
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