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Clinical effectiveness of osteoporosis treatment in older patients: A fracture liaison service-based prospective study

Benedicte Mugnier 1 Aurélie Daumas 2, 3 Anne-Laure Couderc Barbara Mizzi 4 Thomas González Anne Amrani Pierre Lévêque Brice Aymes Jean-Noël Argenson 5 Patrick Villani 6
1 CIML - Centre d'Immunologie de Marseille - Luminy
2 TIMONE - Hôpital de la Timone [CHU - APHM]
3 C2VN - Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research
4 APHM - Assistance Publique - Hôpitaux de Marseille
5 ISM - Institut des Sciences du Mouvement Etienne Jules Marey
6 SESSTIM - U912 INSERM - Aix Marseille Univ - IRD - Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale
Abstract : The clinical efficacy of anti-osteoporotic treatments in old patients is discussed. The aim of this study was to assess if the use of anti-osteoporotic treatments for the secondary prevention of osteoporotic fractures could reduce the risk of refractures in patients over 75 years old in a Fracture Liaison Service. In this population of frail, elderly patients presenting with a recent osteoporotic fracture, we observed that the refracture incidence was similar in the treated group and the untreated group during the first year. However, 30 months after the index fracture, the osteoporosis medication for a year or more reduced the incidence of refractures by 70%.
Keywords : Fracture liaison service older people osteoporotic fracture prevention
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Journal articles
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https://hal-amu.archives-ouvertes.fr/hal-02592951
Contributor : Annick Prémilleux <>
Submitted on : Friday, May 15, 2020 - 4:47:42 PM
Last modification on : Monday, March 29, 2021 - 1:44:08 PM

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UNIV-AMU | ISM-EJM | U1252 | CNRS | INRAE | POLITIQUES-PUBLIQUES

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Benedicte Mugnier, Aurélie Daumas, Anne-Laure Couderc, Barbara Mizzi, Thomas González, et al.. Clinical effectiveness of osteoporosis treatment in older patients: A fracture liaison service-based prospective study. Journal of Women and Aging, Taylor & Francis (Routledge), 2019, 31 (6), pp.553-565. ⟨10.1080/08952841.2018.1529473⟩. ⟨hal-02592951⟩

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