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Community-Based Care in the ANRS-IPERGAY Trial: The Challenges of Combination Prevention

Abstract : ANRS-IPERGAY was a community-based randomized trial investigating the efficacy of sexual activity-based HIV pre-exposure prophylaxis (PrEP) in a population of males and transgender females who had sex with men and were at high risk of HIV infection. We qualitatively analyzed the support provided to participants by community-based health workers (CBHW) throughout the trial's double-blind and open-label extension phases. In particular, we showed that the relationship between participants and CBHW strongly influenced self-managed pill intake. The delicate construction of this relationship, balanced between trust and dependence, played an important role in PrEP adherence. CBHW had to deal with various issues surrounding participants' feelings of empowerment regarding their role in the trial, as well as related tensions between various logics and rationalities. They were essential to participants' continued involvement.
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https://hal-amu.archives-ouvertes.fr/hal-02613517
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Submitted on : Wednesday, May 20, 2020 - 11:01:59 AM
Last modification on : Wednesday, August 19, 2020 - 11:18:14 AM

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Costanza Puppo, Xavier Mabire, Laurent Cotte, Daniela Rojas Castro, Bruno Spire, et al.. Community-Based Care in the ANRS-IPERGAY Trial: The Challenges of Combination Prevention. AIDS Education and Prevention, Guilford Press, 2019, 31 (3), pp.259-272. ⟨10.1521/aeap.2019.31.3.259⟩. ⟨hal-02613517⟩

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