Sensitivity of the Inhomogeneous Magnetization Transfer Imaging Technique to Spinal Cord Damage in Multiple Sclerosis

H. Rasoanandrianina (1, 2) , S. Demortière (1) , A. Trabelsi (1) , J.P. Ranjeva (1, 2) , O. Girard (1) , Guillaume Duhamel (1) , Maxime Guye (1) , Jean Pelletier (1) , Bertrand Audoin (1) , V. Callot (1, 2)

1 CRMBM - Centre de résonance magnétique biologique et médicale
2 LBA UMR T24 - Laboratoire de Biomécanique Appliquée

BACKGROUND AND PURPOSE: The inhomogeneous magnetization transfer technique has demonstrated high specificity for myelin, and has shown sensitivity to multiple sclerosis-related impairment in brain tissue. Our aim was to investigate its sensitivity to spinal cord impairment in MS relative to more established MR imaging techniques (volumetry, magnetization transfer, DTI).

Domains: Life Sciences [q-bio]; Bioengineering; Imaging

H. Rasoanandrianina, S. Demortière, A. Trabelsi, J.P. Ranjeva, O. Girard, et al.. Sensitivity of the Inhomogeneous Magnetization Transfer Imaging Technique to Spinal Cord Damage in Multiple Sclerosis. American Journal of Neuroradiology, 2020, 41 (5), pp.929-937. ⟨10.3174/ajnr.A6554⟩. ⟨hal-02869168⟩