Advancing the understanding of autism disease mechanisms through genetics, Nat Med, vol.22, pp.345-61, 2016. ,
Autism spectrum disorder: insights into convergent mechanisms from transcriptomics, Nat Rev Genet, vol.20, pp.51-63, 2019. ,
Genetics and genomics of psychiatric disease, Science, vol.349, pp.1489-94, 2015. ,
Synaptic, transcriptional and chromatin genes disrupted in autism, Nature, vol.515, pp.209-224, 2014. ,
From the genetic architecture to synaptic plasticity in autism spectrum disorder, Nat Rev Neurosci, vol.16, pp.551-63, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01576592
The human nose harbors a niche of olfactory ectomesenchymal stem cells displaying neurogenic and osteogenic properties, Stem Cells Dev, vol.19, pp.853-66, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-01736210
Multipotent stem cells from adult olfactory mucosa, Dev Dyn, vol.233, pp.496-515, 2005. ,
URL : https://hal.archives-ouvertes.fr/hal-00093306
Olfactory stem cells reveal MOCOS as a new player in autism spectrum disorders, Mol Psychiatry, vol.21, pp.1215-1239, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01787249
Cell biology of molybdenum in plants and humans, Biochim Biophys Acta, vol.1823, pp.1568-79, 2012. ,
Glutathione redox imbalance in brain disorders, Curr Opin Clin Nutr Metab Care, vol.18, pp.89-95, 2015. ,
lincRNAs act in the circuitry controlling pluripotency and differentiation, Nature, vol.477, pp.295-300, 2011. ,
Mechanisms of long non-coding RNAs in mammalian nervous system development, plasticity, disease, and evolution, Neuron, vol.88, pp.861-77, 2015. ,
The non-coding RNA BC1 regulates experience-dependent structural plasticity and learning, Nat Commun, vol.8, p.293, 2017. ,
Long noncoding RNA and its contribution to autism spectrum disorders, CNS Neurosci Ther, vol.23, pp.645-56, 2017. ,
Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism, Nature, vol.540, pp.423-430, 2016. ,
,
, Genome-wide differential expression of synaptic long noncoding RNAs in autism spectrum disorder, Transl Psychiatry, vol.5, p.660, 2015.
Aberrant expression of long noncoding RNAs in autistic brain, J Mol Neurosci, vol.49, pp.589-93, 2013. ,
Functional classification and experimental dissection of long noncoding, RNAs. Cell, vol.172, pp.393-407, 2018. ,
The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution ,
URL : https://hal.archives-ouvertes.fr/hal-01205054
, Genome Res, vol.22, pp.1775-89, 2012.
PhyloCSF: a comparative genomics method to distinguish protein coding and non-coding regions, Bioinforma (Oxf, Engl), vol.27, pp.275-282, 2011. ,
Genomic and transcriptional co-localization of protein-coding and long noncoding RNA pairs in the developing brain, PLoS Genet, vol.5, p.1000617, 2009. ,
The long noncoding RNA Pnky regulates neuronal differentiation of embryonic and postnatal neural stem cells, Cell Stem Cell, vol.16, pp.439-486, 2015. ,
Transcriptomic signatures of neuronal differentiation and their association with risk genes for autism spectrum and related neuropsychiatric disorders, Transl Psychiatry, vol.6, p.864, 2016. ,
A post-transcriptional regulatory switch in polypyrimidine tractbinding proteins reprograms alternative splicing in developing neurons, Genes Dev, vol.21, pp.1636-52, 2007. ,
The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation, Elife, vol.3, p.1201, 2014. ,
PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2, Nat Neurosc, vol.15, pp.381-389, 2012. ,
Integrative genomic analyses for identification and prioritization of long non-coding RNAs associated with autism, PLoS ONE, vol.12, p.178532, 2017. ,
Cellular functions of long noncoding RNAs, Nat Cell Biol, vol.21, pp.542-51, 2019. ,
Single-stranded noncoding RNAs mediate local epigenetic alterations at gene promoters in rat cell lines, J Biol Chem, vol.286, pp.34788-99, 2011. ,
The role of cholesterol metabolism and various steroid abnormalities in autism spectrum disorders: a hypothesis paper, Autism Res, vol.10, pp.1022-1066, 2017. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01577984
Lipid rafts: a signaling platform linking cholesterol metabolism to synaptic deficits in autism spectrum disorders, Front Behav Neurosci, vol.8, p.104, 2014. ,
Brief report: an open-label study of the neurosteroid pregnenolone in adults with autism spectrum disorder, J Autism Dev Disord, vol.44, pp.2971-2978, 2014. ,
Allopregnanolone elevations following pregnenolone administration are associated with enhanced activation of emotion regulation neurocircuits, Biol Psychiatry, vol.73, pp.1045-53, 2013. ,
Cholesterol metabolism and homeostasis in the brain, Protein Cell, vol.6, pp.254-64, 2015. ,
Neurosteroids: biosynthesis and function of these novel neuromodulators, Front Neuroendocrinol, vol.21, pp.1-56, 2000. ,
Multiple mechanisms mediate cholesterol-induced synaptogenesis in a CNS neuron, Mol Cell Neurosci, vol.29, pp.190-201, 2005. ,
URL : https://hal.archives-ouvertes.fr/hal-00094057
Crossregulation and functional redundancy between the splicing regulator PTB and its paralogs nPTB and ROD1, Mol Cell, vol.27, pp.420-454, 2007. ,
Advanced glycation endproducts, dityrosine and arginine transporter dysfunction in autism -a source of biomarkers for clinical diagnosis, Mol Autism, vol.9, p.3, 2018. ,
Autism and oxidative stress interventions: Impact on autistic behavior, Austin J Pharm Ther, vol.2, p.1015, 2014. ,
Metabolic and mitochondrial disorders associated with epilepsy in children with autism spectrum disorder, Epilepsy Behav, vol.47, pp.147-57, 2015. ,
Purine metabolism abnormalities in a hyperuricosuric subclass of autism, Biochim Biophys Acta, vol.1500, pp.291-297, 2000. ,
Antipurinergic therapy for autism-An in-depth review. Mitochondrion, vol.43, pp.1-15, 2018. ,
Pharmacological regulation of oxidative stress in stem cells, Oxid Med Cell Longev, p.4081890, 2018. ,
Differentiation of SH-SY5Y cells to a neuronal phenotype changes cellular bioenergetics and the response to oxidative stress, Free Radic Biol Med, vol.51, pp.2007-2024, 2011. ,
Mutations in human accelerated regions disrupt cognition and social behavior, Cell, vol.167, pp.341-54, 2016. ,