Journal articles
Inequity in access to personalized medicine in France: Evidences from analysis of geo variations in the access to molecular profiling among advanced non-small-cell lung cancer patients: Results from the IFCT Biomarkers France Study
Abstract : In this article, we studied geographic variation in the use of personalized genetic testing for advanced non-small cell lung cancer (NSCLC) and we evaluated the relationship between genetic testing rates and local socioeconomic and ecological variables. We used data on all advanced NSCLC patients who had a genetic test between April 2012 and April 2013 in France in the frame of the IFCT Biomarqueurs-France study (n = 15814). We computed four established measures of geographic variation of the sex-adjusted rates of genetic testing utilization at the "dé partment" (the French territory is divided into 94 administrative units called 'dé partements') level. We also performed a spatial regression model to determine the relationship between dé partement-level sex-adjusted rates of genetic testing utilization and economic and ecological variables. Our results are the following: (i) Overall, 46.87% lung cancer admission patients obtained genetic testing for NSCLC; dé partement-level utilization rates varied over 3.2-fold. Measures of geographic variation indicated a relatively high degree of geographic variation. (ii) there was a statistically significant relationship between genetic testing rates and per capita supply of general practitioners, radiotherapists and PLOS ONE
Cited literature [25 references]
https://hal-amu.archives-ouvertes.fr/hal-02888579
Contributor : l'Houcine Ouafik <>
Submitted on : Friday, July 3, 2020 - 10:17:06 AM
Last modification on : Wednesday, February 24, 2021 - 11:26:05 AM
Long-term archiving on: : Thursday, September 24, 2020 - 6:52:32 AM
Contributor : l'Houcine Ouafik <>
Submitted on : Friday, July 3, 2020 - 10:17:06 AM
Last modification on : Wednesday, February 24, 2021 - 11:26:05 AM
Long-term archiving on: : Thursday, September 24, 2020 - 6:52:32 AM
File
journal.pone.0234387.pdf
Publisher files allowed on an open archive
Licence
Distributed under a Creative Commons Attribution 4.0 International License