A Chemogenetic Tool that Enables Functional Neural Circuit Analysis - Archive ouverte HAL Access content directly
Journal Articles Cell Reports Year : 2020

A Chemogenetic Tool that Enables Functional Neural Circuit Analysis

(1) , (2) , (1, 2) , (1) , (2) , (2) , (2) , (3) , (1) , (2) , (1, 2)
1
2
3

Abstract

Graphical Abstract Highlights d Oxytocin is replaced in its precursor with the insect peptide allatostatin (Ast) d Viral expression induces activity-dependent, synaptic release of bioactive Ast d Ast is expressed in vagal afferents and Ast receptor in Phox2 NTS neurons d This induces a long-term reduction in baroreceptor sensitivity and bodyweight gain
Fichier principal
Vignette du fichier
PIIS2211124720311281.pdf (6.07 Mo) Télécharger le fichier
Origin : Publication funded by an institution
Loading...

Dates and versions

hal-02963987 , version 1 (12-10-2020)

Licence

Attribution - NonCommercial - NoDerivatives - CC BY 4.0

Identifiers

Cite

Hoai Buu Ngo, Mariana R Melo, Ross a D Bathgate, Sharon Layfield, Angela Connelly, et al.. A Chemogenetic Tool that Enables Functional Neural Circuit Analysis. Cell Reports, In press, 32 (11), pp.108139. ⟨10.1016/j.celrep.2020.108139⟩. ⟨hal-02963987⟩
26 View
30 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More