Improved Cervical Cord Lesion Detection with 3D-MP2RAGE Sequence in Patients with Multiple Sclerosis

S. Demortière (1, 2, 3) , P. Lehmann (4) , Jean Pelletier (1, 2, 3) , Bertrand Audoin (1, 2, 3) , Virginie Callot (1, 2)

1 CEMEREM - Centre d'Exploration Métabolique par Résonance Magnétique [Hôpital de la Timone - AP-HM]
2 CRMBM - Centre de résonance magnétique biologique et médicale
3 APHM, Service de Neurologie
4 APHM, Service de Neuroradiologie

Spinal cord lesions have a real diagnostic and prognostic role in multiple sclerosis. Thus, optimizing their detection on MR imaging has become a central issue with direct therapeutic impact. In this study, we compared the 3D-MP2RAGE sequence with the conventional Magnetic Resonance Imaging in Multiple Sclerosis (MAGNIMS) set for cervical cord lesion detection in 28 patients with multiple sclerosis. 3D-MP2RAGE allowed better detection of cervical lesions (+62%) in this population, with better confidence, due to optimized contrast and high spatial resolution

Domains: Life Sciences [q-bio]

S. Demortière, P. Lehmann, Jean Pelletier, Bertrand Audoin, Virginie Callot. Improved Cervical Cord Lesion Detection with 3D-MP2RAGE Sequence in Patients with Multiple Sclerosis. American Journal of Neuroradiology, 2020, 41 (6), pp.1131-1134. ⟨10.3174/ajnr.A6567⟩. ⟨hal-02992331⟩