Uridine Catabolism Breaks the Bonds of Commensalism.

Manish Joshi (1) , Julien Royet (1)

1 IBDM - Institut de Biologie du Développement de Marseille

How gut cells distinguish between beneficial symbionts and deleterious pathobionts is a central question. In this issue of Cell Host & Microbe, Kim et al. (2020) demonstrate that the nucleoside catabolism pathway controlling bacterial uracil and ribose production is an essential trigger of the commensal to pathogen transition.

Domaines: Sciences du Vivant [q-bio]

Manish Joshi, Julien Royet. Uridine Catabolism Breaks the Bonds of Commensalism.. Cell Host and Microbe, 2020, 27 (3), pp.312-314. ⟨10.1016/j.chom.2020.02.008⟩. ⟨hal-03021767⟩