Different sensitivity of CD19-positive bone marrow and lymph node lymphoblasts may cause resistance to blinatumomab in relapsed B-cell acute lymphoblastic leukemia/lymphoma

Vadim Ivanov (1) , Laure Farnault (2) , Cedric Mercier (3) , Cecile Colavolpe (4) , Geoffroy Venton (1) , Julien Colle (5) , Hubert Lepidi (6) , Isabelle Arnoux (7) , Corinne Nicolino-Brunet (2) , Yael Berda-Haddad (8) , Raphaelle Fanciullino , Gleb Ivanov , Regis Costello (3)

1 APHM - Assistance Publique - Hôpitaux de Marseille
2 LA CONCEPTION - Hôpital de la Conception [CHU - APHM]
3 Laboratoire d'hématologie biologique [Hôpital de la Timone - Hôpital Nord - APHM]
4 Service d'Anatomie Pathologique et de Neuropathologie
5 TAGC - Theories and Approaches of Genomic Complexity
6 MEPHI - Microbes évolution phylogénie et infections
7 TIMONE - Hôpital de la Timone [CHU - APHM]
8 Laboratoire de Biologie médicale, AP-HM

Domains: Life Sciences [q-bio]; Microbiology and Parasitology; Bacteriology; Life Sciences [q-bio]; Microbiology and Parasitology; Virology; Life Sciences [q-bio]; Microbiology and Parasitology; Parasitology; Life Sciences [q-bio]; Human health and pathology; Cardiology and cardiovascular system; Life Sciences [q-bio]; Human health and pathology; Emerging diseases; Life Sciences [q-bio]; Human health and pathology; Infectious diseases

Vadim Ivanov, Laure Farnault, Cedric Mercier, Cecile Colavolpe, Geoffroy Venton, et al.. Different sensitivity of CD19-positive bone marrow and lymph node lymphoblasts may cause resistance to blinatumomab in relapsed B-cell acute lymphoblastic leukemia/lymphoma. Leukemia & lymphoma, 2020, 61 (5), pp.1230-1233. ⟨10.1080/10428194.2019.1706737⟩. ⟨hal-03159741⟩