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Granulocyte Macrophage Colony-Stimulating Factor-Specific Autoantibodies and Cerebral Nocardia With Pulmonary Alveolar Proteinosis

Abstract : Abstract In this study, we report the history of a 40-year-old man with a primary cerebral abscess caused by Nocardia abscessus that led to the discovery of autoimmune pulmonary alveolar lipoproteinosis (anti-granulocyte-macrophage colony-stimulating factor [GM-CSF] autoantibodies). Anti-GM-CSF autoantibodies promote immunodeficiency and should be monitored to prevent opportunistic and disseminated infections and to diagnose asymptomatic pulmonary alveolar lipoproteinosis.
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https://hal-amu.archives-ouvertes.fr/hal-03279641
Contributor : Isabelle Combe <>
Submitted on : Tuesday, September 14, 2021 - 12:44:15 PM
Last modification on : Wednesday, September 15, 2021 - 1:43:58 PM

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Charlotte Berthoux, Morgane Mailhe, Frédéric Vély, Clarisse Gauthier, Jean-Louis Mège, et al.. Granulocyte Macrophage Colony-Stimulating Factor-Specific Autoantibodies and Cerebral Nocardia With Pulmonary Alveolar Proteinosis. Open Forum Infectious Diseases, Oxford University Press, 2021, 8 (2), ⟨10.1093/ofid/ofaa612⟩. ⟨hal-03279641⟩

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