Contagion Management at the Méditerranée Infection University Hospital Institute

Pierre-Edouard Fournier (1, 2) , Sophie Edouard (3, 2) , Nathalie Wurtz (3, 2) , Justine Raclot (2) , Marion Bechet (2) , Christine Zandotti (4, 2) , Véronique Filosa (2) , Didier Raoult (3, 2) , Florence Fenollar (1, 2)

1 VITROME - Vecteurs - Infections tropicales et méditerranéennes
2 IHU Marseille - Institut Hospitalier Universitaire Méditerranée Infection
3 MEPHI - Microbes évolution phylogénie et infections
4 UVE - Unité des Virus Emergents

The Méditerranée Infection University Hospital Institute (IHU) is located in a recent building, which includes experts on a wide range of infectious disease. The IHU strategy is to develop innovative tools, including epidemiological monitoring, point-of-care laboratories, and the ability to mass screen the population. In this study, we review the strategy and guidelines proposed by the IHU and its application to the COVID-19 pandemic and summarise the various challenges it raises. Early diagnosis enables contagious patients to be isolated and treatment to be initiated at an early stage to reduce the microbial load and contagiousness. In the context of the COVID-19 pandemic, we had to deal with a shortage of personal protective equipment and reagents and a massive influx of patients. Between 27 January 2020 and 5 January 2021, 434,925 nasopharyngeal samples were tested for the presence of SARS-CoV-2. Of them, 12,055 patients with COVID-19 were followed up in our out-patient clinic, and 1888 patients were hospitalised in the Institute. By constantly adapting our strategy to the ongoing situation, the IHU has succeeded in expanding and upgrading its equipment and improving circuits and flows to better manage infected patients.

Mots clés: contagion; institut hospitalo-universitaire méditerranée infection; SARS-CoV-2; COVID-19; diagnosis; rapid diagnostic test; point-of-care

Domaines: Bactériologie; Cardiologie et système cardiovasculaire; Maladies émergentes; Maladies infectieuses; Parasitologie; Virologie

Pierre-Edouard Fournier, Sophie Edouard, Nathalie Wurtz, Justine Raclot, Marion Bechet, et al.. Contagion Management at the Méditerranée Infection University Hospital Institute. Journal of Clinical Medicine, 2021, 10 (12), pp.2627. ⟨10.3390/jcm10122627⟩. ⟨hal-03333908⟩