Skip to Main content Skip to Navigation
Journal articles

Antimicrobial Peptides: A Potent Alternative to Antibiotics

Abstract : Antimicrobial peptides constitute one of the most promising alternatives to antibiotics since they could be used to treat bacterial infections, especially those caused by multidrug-resistant pathogens. Many antimicrobial peptides, with various activity spectra and mechanisms of actions, have been described. This review focuses on their use against ESKAPE bacteria, especially in biofilm treatments, their synergistic activity, and their application as prophylactic agents. Limitations and challenges restricting therapeutic applications are highlighted, and solutions for each challenge are evaluated to analyze whether antimicrobial peptides could replace antibiotics in the near future.
Document type :
Journal articles
Complete list of metadata
Contributor : Ludovic Leloup Connect in order to contact the contributor
Submitted on : Monday, March 7, 2022 - 11:02:28 PM
Last modification on : Friday, April 1, 2022 - 3:54:59 AM
Long-term archiving on: : Wednesday, June 8, 2022 - 9:46:51 PM


Publisher files allowed on an open archive


Distributed under a Creative Commons Attribution 4.0 International License



Mariam Rima, Mohamad Rima, Ziad Fajloun, Jean-Marc Sabatier, Burkhard Bechinger, et al.. Antimicrobial Peptides: A Potent Alternative to Antibiotics. Antibiotics, 2021, 10 (9), pp.1095. ⟨10.3390/antibiotics10091095⟩. ⟨hal-03357922⟩



Record views


Files downloads