Effects of X-ray, electron beam and gamma irradiation on PE/EVOH/PE multilayer film properties

Nina Girard-Perier (1) , Magalie Claeys-Bruno (2) , Sylvain Marque (1) , Nathalie Dupuy (2) , Fanny Gaston (3) , Samuel Dorey (3)

1 ICR - Institut de Chimie Radicalaire
2 IMBE - Institut méditerranéen de biodiversité et d'écologie marine et continentale
3 Sartorius Stedim France S.A.S. [Aubagne]

To increase sterilization capacity, X-ray and e-beam irradiation modalities are more and more attractive for the indutrial sterilization of heathcare products (medical devices and biopharmaceutical goods). However, no study comparing these different techniques are available concerning multi-layer films. Thus, with the PE/EVOH/PE multilayer film as a model, we show that, whatever the modality of irradiation, the thermal properties are not significantly changed as shown by DSC, and, as such, the physical and mechanical properties of this material are also expected to behave similarly. On the other hand, chemical properties such as oxidation ability are strikingly modified, i.e., the same oxidation level for X-ray and γ-irradiation and twice weaker for e-beam irradiation.

Domaines: Physique [physics]

Nina Girard-Perier, Magalie Claeys-Bruno, Sylvain Marque, Nathalie Dupuy, Fanny Gaston, et al.. Effects of X-ray, electron beam and gamma irradiation on PE/EVOH/PE multilayer film properties. Chemical Communications, 2021, 57 (84), pp.11049-11051. ⟨10.1039/d1cc02871e⟩. ⟨hal-03395185⟩