Vaginal NOTES approach for risk-reducing salpingo-oophorectomy in BRCA mutation carriers: A video demonstration

Antoine Netter (1, 2) , Raphael Niddam (2) , Aubert Agostini (2) , Patrice Crochet (2)

1 IMBE - Institut méditerranéen de biodiversité et d'écologie marine et continentale
2 Department of Obstetrics and Gynecology, Assistance Publique H^opitaux de Marseille, La Conception Hospital, 13005 Marseille, Aix Marseille University, France

Risk-reducing bilateral salpingo-oophorectomy (BSO) is an important option to prevent the development of ovarian and fallopian tube cancers in women with a BRCA1/2 mutation. Conventional laparoscopy is the current preferred technique since it is associated with less morbidity compared to laparotomy. Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) is a new minimally invasive technique that allows access to the peritoneal cavity through the vagina without skin incisions. The vNOTES technique for risk-reducing BSO is presented herein. This article includes a narrated, step-by-step video demonstration of the entire procedure. Risk-reducing BSO using the vNOTES approach is a feasible technique that appears to be simple, safe, and reproducible. This technique has the potential to improve patients’ surgical experience and provide good long-term functional and cosmetics outcomes. This technique needs to be further evaluated and compared to the conventional laparoscopic approach.

Keywords: vNOTES technique; Natural orifice transluminal endoscopic surgery; Bilateral salpingo-oophorectomy; Risk reducing surgery; BRCA; Surgical education

Domains: Humanities and Social Sciences

Antoine Netter, Raphael Niddam, Aubert Agostini, Patrice Crochet. Vaginal NOTES approach for risk-reducing salpingo-oophorectomy in BRCA mutation carriers: A video demonstration. Journal of Gynecology Obstetrics and Human Reproduction, 2021, 50 (10), pp.102212. ⟨10.1016/j.jogoh.2021.102212⟩. ⟨hal-03400652⟩