TAFA4 relieves injury-induced mechanical hypersensitivity through LDL receptors and modulation of spinal A-type K+ current - Archive ouverte HAL Access content directly
Journal Articles Cell Reports Year : 2021

TAFA4 relieves injury-induced mechanical hypersensitivity through LDL receptors and modulation of spinal A-type K+ current

Abstract

Highlights d TAFA4 reverses inflammatory, postoperative, and nerve injury-induced mechanical pain d TAFA4-mediated antihypersensitive effect requires functional LDL receptor family members d SNI alters spinal I A in opposite direction in excitatory and inhibitory interneurons d TAFA4 reverses SNI-induced alteration of I A in both interneuron subtypes
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Dates and versions

hal-03406182 , version 1 (27-10-2021)

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Attribution - NonCommercial - NoDerivatives - CC BY 4.0

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Sungjae Yoo, Catarina Santos, Ana Reynders, Irène Marics, Pascale Malapert, et al.. TAFA4 relieves injury-induced mechanical hypersensitivity through LDL receptors and modulation of spinal A-type K+ current. Cell Reports, 2021, 37 (4), pp.109884. ⟨10.1016/j.celrep.2021.109884⟩. ⟨hal-03406182⟩
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