Helical Bisphosphinites in Asymmetric Tsuji‐Trost Allylation: a Remarkable P:Pd Ratio Effect - Aix-Marseille Université Accéder directement au contenu
Article Dans Une Revue ChemCatChem Année : 2021

Helical Bisphosphinites in Asymmetric Tsuji‐Trost Allylation: a Remarkable P:Pd Ratio Effect

Résumé

This article discloses a study on a chiral bis-phosphorylated-helical ligand in the palladium-catalyzed Tsuji-Trost allylation. The use of 2,15-bisphosphinite[6]helicenes allowed to evidence a remarkable ligand effect, in which the (R) and (S) isomeric products can be selectively formed as a direct function of the amount of ligand introduced. Study of the organometallic species involved through 31P NMR analysis of a model complex and X-Ray diffraction analysis together with DFT calculations shed light on this phenomenon.

Domaines

Catalyse
Fichier principal
Vignette du fichier
CCTC-S-21-01317.pdf (1.83 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-03420672 , version 1 (09-11-2021)

Identifiants

Citer

Caleb Medena, Corinne Aubert, Etienne Derat, Louis Fensterbank, Geoffrey Gontard, et al.. Helical Bisphosphinites in Asymmetric Tsuji‐Trost Allylation: a Remarkable P:Pd Ratio Effect. ChemCatChem, 2021, 13 (21), pp.4543-4548. ⟨10.1002/cctc.202101072⟩. ⟨hal-03420672⟩
49 Consultations
83 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More