Early combination therapy with hydroxychloroquine and azithromycin reduces mortality in 10,429 COVID-19 outpatients

Matthieu Million (1, 2) , Jean-Christophe Lagier (1, 2) , Hervé Tissot-Dupont (1, 2) , Isabelle Ravaux (2) , Catherine Dhiver (2) , Christelle Tomei (2) , Nadim Cassir (2) , Léa Delorme (2) , Sébastien Cortaredona (3, 2) , Sophie Amrane (1, 2) , Camille Aubry (2) , Karim Bendamardji (2) , Cyril Berenger (2) , Barbara Doudier (2) , Sophie Edouard (2, 1) , Marie Hocquart (2) , Morgane Mailhe (2) , Coralie Porcheto (2) , Piseth Seng (2) , Catherine Triquet (2) , Stéphanie Gentile (4) , Elisabeth Jouve (4) , Audrey Giraud-Gatineau (2, 3) , Herve Chaudet (2, 3) , Laurence Camoin-Jau (2, 1) , Philippe Colson (2, 1) , Philippe Gautret (2, 3) , Pierre-Edouard Fournier (2, 3) , Baptiste Maille (5) , Jean-Claude Deharo (5) , Paul Habert (6, 7, 8) , Jean-Yves Gaubert (6, 7, 8) , Alexis Jacquier (6) , Stéphane Honore (9) , Katell Guillon-Lorvellec (2, 1) , Yolande Obadia (2, 3) , Philippe Parola (2, 3) , Philippe Brouqui (2, 3) , Didier Raoult (2, 1)

1 MEPHI - Microbes évolution phylogénie et infections
2 IHU Marseille - Institut Hospitalier Universitaire Méditerranée Infection
3 VITROME - Vecteurs - Infections tropicales et méditerranéennes
4 CEReSS - Centre d'études et de recherche sur les services de santé et la qualité de vie
5 C2VN - Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research
6 CERIMED - Centre Européen de Recherche en Imagerie médicale
7 LIIE - Laboratoire d'Imagerie Interventionnelle Expérimentale
8 Département de Radiologie [Hôpital de la Timone - APHM]
9 Laboratoire de Pharmacie Clinique, CHU Timone

Domains: Life Sciences [q-bio]; Microbiology and Parasitology; Bacteriology; Life Sciences [q-bio]; Microbiology and Parasitology; Virology; Life Sciences [q-bio]; Microbiology and Parasitology; Parasitology; Life Sciences [q-bio]; Human health and pathology; Cardiology and cardiovascular system; Life Sciences [q-bio]; Human health and pathology; Emerging diseases; Life Sciences [q-bio]; Human health and pathology; Infectious diseases

Matthieu Million, Jean-Christophe Lagier, Hervé Tissot-Dupont, Isabelle Ravaux, Catherine Dhiver, et al.. Early combination therapy with hydroxychloroquine and azithromycin reduces mortality in 10,429 COVID-19 outpatients. Reviews in Cardiovascular Medicine, 2021, 22 (3), pp.1063. ⟨10.31083/j.rcm2203116⟩. ⟨hal-03436273⟩