Efficacy and safety of regorafenib compared to placebo and to post-cross-over regorafenib in advanced non-adipocytic soft tissue sarcoma

Christine Desmedt (1) , Roberto Salgado (1) , Marco Fornili (2) , Giancarlo Pruneri (3) , Gert van den Eynden , Gabriele Zoppoli (4) , Françoise Rothé , Laurence Buisseret , Soizic Garaud (5) , Karen Willard-Gallo (6) , David Brown (7) , Yacine Bareche (8) , Ghizlane Rouas (6) , Christine Galant (9) , Sherene Loi (1) , Giuseppe Viale (10) , Angelo Di Leo (11) , Andrew Green (12) , Ian Ellis , Emad Rakha , Denis Larsimont , Elia Biganzoli , Christos Sotiriou , Thomas Brodowicz (13) , Olivier Mir (14) , Jennifer Wallet (15) , Antoine Italiano (16) , Jean-Yves Blay (17) , François Bertucci (18) , Wolfgang Eisterer , Christine Chevreau (19) , Sophie Piperno-Neumann (20) , Emmanuelle Bompas (21) , Thomas Ryckewaert (22) , Bernadette Liegl-Antzwager , Julien Thery , Nicolas Penel (23) , Axel Le Cesne (14) , Marie-Cécile Le Deley

1 Breast Cancer Translational Research Laboratory
2 University of Pisa - Università di Pisa
3 ESMO - European Institute of Oncology [Milan]
4 IRCCS Ospedale Policlinico San Martino [Genoa, Italy]
5 EA2216 - Immunologie et Pathologie
6 Institut Jules Bordet [Bruxelles]
7 IMN - Institut des Matériaux Jean Rouxel
8 IGMM - Institut de Génétique Moléculaire de Montpellier
9 Cliniques Universitaires Saint-Luc [Bruxelles]
10 Division of Pathology and Laboratory Medicine
11 Translational Research Unit c/o Department of Oncology, Hospital of Prato
12 ACoRD - Academic Centre on Rare Diseases
13 Université médicale de Vienne, Autriche
14 Sarcome
15 CHRU Lille - Centre Hospitalier Régional Universitaire [Lille]
16 Institut Bergonié [Bordeaux]
17 Centre Léon Bérard [Lyon]
18 CRCM - Centre de Recherche en Cancérologie de Marseille
19 IUCT Oncopole - UMR 1037 - Institut Universitaire du Cancer de Toulouse - Oncopole
20 Département d'Oncologie Médicale [Institut Curie, Paris]
21 Département d'oncologie médicale [ICO, Saint Herblain]
22 Département d'oncologie médicale
23 Ecole de Médecine [CHRU Lille]

Domains: Life Sciences [q-bio]; Cancer

Christine Desmedt, Roberto Salgado, Marco Fornili, Giancarlo Pruneri, Gert van den Eynden, et al.. Efficacy and safety of regorafenib compared to placebo and to post-cross-over regorafenib in advanced non-adipocytic soft tissue sarcoma. European Journal of Cancer, 2018, 99 (7), pp.28-36. ⟨10.1016/j.ejca.2018.05.008⟩. ⟨hal-03623702⟩