Steroid-Fullerene hybrids: A review
Résumé
Among carbon-based materials, fullerenes have emerged as very fascinating nanocarbons on account of the interesting properties and applications of some of their derivatives in medicine or materials chemistry. The low solubility of C 60 , the most famous family member, has limited its use in medicinal chemistry but its covalent functionalization with different moieties such as porphyrins or other bioactive molecules changes its physicochemical properties, such as its solubility and biocompatibility. New hybrid compounds, bearing fullerene and steroid units in the same molecule can be regarded as promising functional chimeras with encouraging biomedical applications and have become a topic of considerable interest in the last few years. Recent developments in the syntheses of steroid-fullerene hybrids are described herein.
Domaines
Matériaux
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