Combined Anakinra and Ruxolitinib treatment to rescue extremely ill COVID-19 patients: A pilot study.

Gilles Kaplanski (1, 2) , Denis Bontemps (3, 4) , Pierre Esnault (5) , Valery Blasco (6) , Julien Carvelli (6, 7) , David Delarbre (5) , Raphael Cauchois (2, 7) , Jean-Marie Forel (3, 4) , Laurent Papazian (3, 4)

1 C2VN - Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research
2 LA CONCEPTION - Hôpital de la Conception [CHU - APHM]
3 Hôpital Nord [CHU - APHM]
4 CEReSS - Centre d'études et de recherche sur les services de santé et la qualité de vie
5 HIA - Hopital d'instruction des armées Sainte-Anne [Toulon]
6 TIMONE - Hôpital de la Timone [CHU - APHM]
7 AMU - Aix Marseille Université

No abstract available

Keywords: Acute respiratory failure; Anakinra; COVID 19; Hyperinflammation; Invasive mechanical ventilation; Ruxolitinib

Domains: Life Sciences [q-bio]

Gilles Kaplanski, Denis Bontemps, Pierre Esnault, Valery Blasco, Julien Carvelli, et al.. Combined Anakinra and Ruxolitinib treatment to rescue extremely ill COVID-19 patients: A pilot study.. Autoimmunity Reviews, 2021, 20 (2), pp.102726. ⟨10.1016/j.autrev.2020.102726⟩. ⟨hal-03653474⟩