A short review on selena and tellurasteroids
Abstract
Recently hetero steroids have received much attention for pharmacological interest. Indeed, the replacement of one or more carbon atoms of a steroid molecule by a heteroatom often results in useful alterations to its biological activity because this modification affects the chemical properties of this steroid. Compounds containing a selenium, or a tellurium atom can possess biological properties and so have a great potential for the creation of a new library of molecules important for biological applications. Some of them have been used as antibacterial, antiviral, antihypertensive, or chemopreventive anticancer agents. Recent developments in the syntheses of selena and tellurasteroids are described herein.
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