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Journal Articles RSC Advances Year : 2022

Ultrasonic-assisted-synthesis of isoindolin-1-one derivatives


A small library of 3-hydroxyisoindolin-1-ones has been prepared from 3-alkylidenephtalides under ultrasonic irradiation. This practical synthesis is featured by group tolerance, high efficiency and yields. The reaction can also be performed in multigram scale and be further extended to access other motifs of isoindolin-1-ones in a one-pot fashion.
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hal-03862577 , version 1 (21-11-2022)



Muhammad Idham Darussalam Mardjan, Muhamad Fadhly Hariadi, Indah Mutiara Putri, Nilna Amalia Musyarrofah, Muflihah Salimah, et al.. Ultrasonic-assisted-synthesis of isoindolin-1-one derivatives. RSC Advances, 2022, 12 (29), pp.19016-19021. ⟨10.1039/d2ra02720h⟩. ⟨hal-03862577⟩


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