Glial Modulation of Energy Balance: The Dorsal Vagal Complex Is No Exception - Archive ouverte HAL Access content directly
Journal Articles International Journal of Molecular Sciences Year : 2022

Glial Modulation of Energy Balance: The Dorsal Vagal Complex Is No Exception

(1) , (1) , , (1) , (1) , (1)
1

Abstract

The avoidance of being overweight or obese is a daily challenge for a growing number of people. The growing proportion of people suffering from a nutritional imbalance in many parts of the world exemplifies this challenge and emphasizes the need for a better understanding of the mechanisms that regulate nutritional balance. Until recently, research on the central regulation of food intake primarily focused on neuronal signaling, with little attention paid to the role of glial cells. Over the last few decades, our understanding of glial cells has changed dramatically. These cells are increasingly regarded as important neuronal partners, contributing not just to cerebral homeostasis, but also to cerebral signaling. Our understanding of the central regulation of energy balance is part of this (r)evolution. Evidence is accumulating that glial cells play a dynamic role in the modulation of energy balance. In the present review, we summarize recent data indicating that the multifaceted glial compartment of the brainstem dorsal vagal complex (DVC) should be considered in research aimed at identifying feeding-related processes operating at this level.

Dates and versions

hal-03872386 , version 1 (25-11-2022)

Identifiers

Cite

Jean-Denis Troadec, Stéphanie Gaigé, Manon Barbot, Bruno Lebrun, Rym Barbouche, et al.. Glial Modulation of Energy Balance: The Dorsal Vagal Complex Is No Exception. International Journal of Molecular Sciences, 2022, 23 (2), pp.960. ⟨10.3390/ijms23020960⟩. ⟨hal-03872386⟩
0 View
0 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More