Inhomogeneous Magnetization Transfer (ihMT) imaging in the acute cuprizone mouse model of demyelination/remyelination

Andreea Hertanu (1, 2) , Lucas Soustelle (1, 2) , Julie Buron (3, 1, 2) , Julie Le Priellec (3) , Myriam Cayre (3) , Arnaud Le Troter (1, 2) , Valentin H Prevost (1, 2) , Jean-Philippe Ranjeva (1, 2) , Gopal Varma (4) , David C Alsop (4) , Pascale Durbec (3) , Olivier M Girard (1, 2) , Guillaume Duhamel (1, 2)

1 CRMBM - Centre de résonance magnétique biologique et médicale
2 AP-HM, Pôle d'imagerie médicale, Hôpital de la Timone, CEMEREM, Marseille, France
3 IBDM - Institut de Biologie du Développement de Marseille
4 BIDMC - Beth Israel Deaconess Medical Center [Boston]

(G. Duhamel). acteristic of tissues with motion-restricted molecules and unaveraged dipolar interactions (Varma et al., 2015). Hence the ihMT signal provides access to a new contrast weighted by the dipolar order relaxation time T 1D (Varma et al., 2017), a probe for tissue microstructure

Domains: Life Sciences [q-bio]; Bioengineering; Imaging

Andreea Hertanu, Lucas Soustelle, Julie Buron, Julie Le Priellec, Myriam Cayre, et al.. Inhomogeneous Magnetization Transfer (ihMT) imaging in the acute cuprizone mouse model of demyelination/remyelination. NeuroImage, 2023, 265, ⟨10.1016/j.neuroimage.2022.119785⟩. ⟨hal-03906754⟩