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Journal Articles Neuropathology and Applied Neurobiology Year : 2022

The genomic landscape of dysembryoplastic neuroepithelial tumours and a comprehensive analysis of recurrent cases

Mélanie Pagès
  • Function : Author
Marie-Anne Debily
  • Function : Author
Frédéric Fina
  • Function : Author
David Jones
  • Function : Author
Raphael Saffroy
  • Function : Author
David Castel
  • Function : Author
Thomas Blauwblomme
  • Function : Author
Alice Métais
  • Function : Author
Marie Bourgeois
  • Function : Author
Emmanuèle Lechapt-Zalcman
  • Function : Author
Arnault Tauziède-Espariat
  • Function : Author
Felipe Andreiuolo
  • Function : Author
Fabrice Chrétien
  • Function : Author
Jacques Grill
  • Function : Author
Nathalie Boddaert
  • Function : Author
Rameen Beroukhim
  • Function : Author
Pascale Varlet
  • Function : Author
Marie‐anne Debily
  • Function : Author

Abstract

Dysembryoplastic neuroepithelial tumour (DNT) is a glioneuronal tumour that is challenging to diagnose, with a wide spectrum of histological features. Three histopathological patterns have been described: specific DNTs (both the simple form and the complex form) comprising the specific glioneuronal element, and also the non-specific/diffuse form which lacks it, and has unclear phenotype-genotype correlations with numerous differential diagnoses.

Dates and versions

hal-03982369 , version 1 (10-02-2023)

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Mélanie Pagès, Marie-Anne Debily, Frédéric Fina, David Jones, Raphael Saffroy, et al.. The genomic landscape of dysembryoplastic neuroepithelial tumours and a comprehensive analysis of recurrent cases. Neuropathology and Applied Neurobiology, 2022, 48 (6), pp.e12834. ⟨10.1111/nan.12834⟩. ⟨hal-03982369⟩
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