Skip to Main content Skip to Navigation
Journal articles

Catalyst- and Halogen-Free Regioselective Friedel-Crafts alpha-Ketoacylations

Kishor Mohanan 1 Marc Presset 1 Damien Mailhol 1 Yoann Coquerel 1 Jean Rodriguez 1 
1 STeRéO
ISM2 - Institut des Sciences Moléculaires de Marseille
Abstract : Highly regio- selective and efficient catalyst- and halogen-free Friedel-Crafts alpha-ketoacy- lation reactions leading to heterocycles functionalized with a very versatile 1,3- diketone moiety are described. The reactions rely on microwave-assisted domino Wolff rearrangement/Friedel- Crafts sequences from 2-diazo-1,3- diketones via transient, highly reactive alpha-keto ketene intermediates.
Document type :
Journal articles
Complete list of metadata

https://hal.archives-ouvertes.fr/hal-00736640
Contributor : Gaelle Chouraqui Connect in order to contact the contributor
Submitted on : Friday, September 28, 2012 - 4:49:00 PM
Last modification on : Tuesday, December 14, 2021 - 8:36:12 AM

Links full text

Identifiers

Collections

Citation

Kishor Mohanan, Marc Presset, Damien Mailhol, Yoann Coquerel, Jean Rodriguez. Catalyst- and Halogen-Free Regioselective Friedel-Crafts alpha-Ketoacylations. Chemistry - A European Journal, Wiley-VCH Verlag, 2012, 18, pp.9217-9220. ⟨10.1002/chem.201201027⟩. ⟨hal-00736640⟩

Share

Metrics

Record views

18