Spatio-temporal Patterns and Landscape-Associated Risk of Buruli Ulcer in Akonolinga, Cameroon

Jordi Landier (1, 2) , Jean Gaudart (3, 4) , Kevin Carolan (2) , D Lo Seen (1) , Jean-François Guégan (5) , Sara Eyangoh (1) , Arnaud Fontanet (6, 2) , Gaëtan Texier (1, 3)

1 Centre Pasteur du Cameroun
2 Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology
3 SESSTIM - U912 INSERM - Aix Marseille Univ - IRD - Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale
4 AMU - Aix Marseille Université
5 MIVEGEC - Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle
6 CNAM - Conservatoire National des Arts et Métiers [CNAM]

Background: Buruli ulcer (BU) is an extensively damaging skin infection caused by Mycobacterium ulcerans, whose transmission mode is still unknown. The focal distribution of BU and the absence of interpersonal transmission suggest a major role of environmental factors, which remain unidentified. This study provides the first description of the spatio-temporal variations of BU in an endemic African region, in Akonolinga, Cameroon. We quantify landscape-associated risk of BU, and reveal local patterns of endemicity.

Domains: Mathematics [math]; Dynamical Systems [math.DS]; Mathematics [math]; Probability [math.PR]; Life Sciences [q-bio]; Santé publique et épidémiologie; Statistics [stat]; Applications [stat.AP]; Statistics [stat]; Methodology [stat.ME]; Mathematics [math]; Statistics [math.ST]; Environmental Sciences; Environmental and Society; Life Sciences [q-bio]; Ecology, environment; Health; Life Sciences [q-bio]; Human health and pathology; Infectious diseases; Life Sciences [q-bio]; Human health and pathology; Emerging diseases; Life Sciences [q-bio]; Microbiology and Parasitology; Parasitology

Jordi Landier, Jean Gaudart, Kevin Carolan, D Lo Seen, Jean-François Guégan, et al.. Spatio-temporal Patterns and Landscape-Associated Risk of Buruli Ulcer in Akonolinga, Cameroon. PLoS Neglected Tropical Diseases, 2014, ⟨10.1371/journal.pntd.0003123⟩. ⟨hal-01307475⟩