Journal articles
LedPred: an R/bioconductor package to predict regulatory sequences using support vector machines
Abstract : Supervised classification based on support vector machines (SVMs) has successfully been used for the prediction of cis-regulatory modules (CRMs). However, no integrated tool using such heterogeneous data as position-specific scoring matrices, ChIP-seq data or conservation scores is currently available. Here, we present LedPred, a flexible SVM workflow that predicts new regulatory sequences based on the annotation of known CRMs, which are associated to a large variety of feature types. LedPred is provided as an R/Bioconductor package connected to an online server to avoid installation of non-R software. Due to the heterogeneous CRM feature integration, LedPred excels at the prediction of regulatory sequences in Drosophila and mouse datasets compared with similar SVM-based software.
https://hal-amu.archives-ouvertes.fr/hal-01460122
Contributor : Lionel Spinelli Connect in order to contact the contributor
Submitted on : Tuesday, February 7, 2017 - 4:00:07 PM
Last modification on : Friday, November 26, 2021 - 10:56:04 AM
Contributor : Lionel Spinelli Connect in order to contact the contributor
Submitted on : Tuesday, February 7, 2017 - 4:00:07 PM
Last modification on : Friday, November 26, 2021 - 10:56:04 AM
Links full text
