Skip to Main content Skip to Navigation
Journal articles

Characterization of insoluble calcium alginates by solid-state NMR

Giulia Mollica 1 Fabio Ziarelli 2 Stephane Lack Florence Brunel Stéphane Viel 1
1 ICR - Institut de Chimie Radicalaire
2 AMU SPEC - Spectropôle - Aix Marseille Université
Abstract : Three series of 9 insoluble calcium alginate powders with different average calcium contents (1.5, 3.5 and 8%, w/w) are investigated by means of C-13 solid-state NMR spectroscopy. The effect of the increased calcium content on the determination of the mannuronate (M) to guluronate (G) ratio from spectral deconvolution of the C-13 CP/MAS spectra is discussed, and the variations observed are commented in function of possible structural modifications related to the interaction with the divalent cations. The possibility fusing solid-state NMR spectroscopy for the quantification of the calcium content in unknown alginate samples is explored performing principal component analysis (PCA) of the spectra. The results obtained show that: a clear separation of alginates with slightly different calcium content is possible. The proposed method relies on the sole use of the chemical shifts of the signals corresponding to pyranose carbons, suggesting that PCA of solid-state NMR data holds promises as a rapid and undestructive method for screening the calcium content of alginate-based materials with biomedical uses. (C) 2011 Elsevier Ltd. All rights reserved.
Document type :
Journal articles
Complete list of metadatas
https://hal-amu.archives-ouvertes.fr/hal-01460409
Contributor : Didier Gigmes <>
Submitted on : Tuesday, February 7, 2017 - 4:39:26 PM
Last modification on : Wednesday, March 7, 2018 - 9:34:02 AM

Identifiers

Collections

UNIV-AMU | CNRS | INC-CNRS

Citation

Giulia Mollica, Fabio Ziarelli, Stephane Lack, Florence Brunel, Stéphane Viel. Characterization of insoluble calcium alginates by solid-state NMR. Carbohydrate Polymers, Elsevier, 2012, 87 (1), pp.383--391. ⟨10.1016/j.carbpol.2011.07.066⟩. ⟨hal-01460409⟩

Export

BibTeX TEI DC DCterms EndNote

Share

Metrics

Record views

165