Micelle-Based Adjuvants for Subunit Vaccine Delivery - Archive ouverte HAL Access content directly
Journal Articles Vaccines Year : 2015

Micelle-Based Adjuvants for Subunit Vaccine Delivery


In the development of subunit vaccines with purified or recombinant antigens for cancer and infectious diseases, the design of improved and safe adjuvants able to efficiently target the antigen presenting cells, such as dendritic cells, represents a crucial challenge. Nanoparticle-based antigen delivery systems have been identified as an innovative strategy to improve the efficacy of subunit vaccines. Among them, self-assembled micellar nanoparticles from amphiphilic (macro)molecules have recently emerged as promising candidates. In this short review, we report on the recent research findings highlighting the versatility and potential of such systems in vaccine delivery.

Dates and versions

hal-01460651 , version 1 (07-02-2017)



Thomas Trimaille, Bernard Verrier. Micelle-Based Adjuvants for Subunit Vaccine Delivery. Vaccines, 2015, 3 (4), pp.803--813. ⟨10.3390/vaccines3040803⟩. ⟨hal-01460651⟩
38 View
0 Download



Gmail Facebook Twitter LinkedIn More