Skip to Main content Skip to Navigation
Journal articles

SynTarget: an online tool to test the synergetic effect of genes on survival outcome in cancer

Abstract : The identification of target combinationswith synergistic effects on cancer is at the leading edge of modern cancer research, especially for the development of combined anticancer therapies. However, at present, the basis for selection of beneficial target combinations commonly relies on expert opinion without any systematic rationale. The development of high-throughput technologies has led to the availability of large-scale clinical gene expression data sets.2–4Mining of these data sets for identification of gene combinations with synergetic effects on survival outcome in cancer could provide a systematic rationale for the identification of target combinations with potential therapeutic synergy. ...
Complete list of metadatas

https://hal-amu.archives-ouvertes.fr/hal-01478693
Contributor : François Devred <>
Submitted on : Tuesday, February 28, 2017 - 11:57:01 AM
Last modification on : Saturday, October 3, 2020 - 3:21:02 AM
Long-term archiving on: : Monday, May 29, 2017 - 1:38:00 PM

File

SynTarget_an_online_tool_to_te...
Explicit agreement for this submission

Identifiers

Collections

Citation

Ivano Amelio, Philipp Tsvetkov, R.A. Knight, A Lisitsa, G Melino, et al.. SynTarget: an online tool to test the synergetic effect of genes on survival outcome in cancer. Cell Death and Differentiation, Nature Publishing Group, 2016, 23 (5), pp.912. ⟨10.1038/cdd.2016.12⟩. ⟨hal-01478693⟩

Share

Metrics

Record views

178

Files downloads

314