Taxonogenomic description of four new Clostridium species isolated from human gut : 'Clostridium amazonitimonense', 'Clostridium merdae', 'Clostridium massilidielmoense' and 'Clostridium nigeriense'.

M. T. Alou (1) , S. Ndongo (1) , L. Fregere (1) , N. Labas (1) , C. Andrieu (1) , M. Richez (2) , C. Couderc (2) , J.-P. Baudoin (2) , J. Abrahao (3) , S. Brah , A. Diallo (1) , C. Sokhna (4) , N. Cassir (1) , B. La Scola (2) , F. Cadoret (2) , Didier Raoult (2)

1 URMITE - Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes
2 MEPHI - Microbes évolution phylogénie et infections
3 UFMG - Universidade Federal de Minas Gerais [Belo Horizonte]
4 VITROME - Vecteurs - Infections tropicales et méditerranéennes

Culturomics investigates microbial diversity of the human microbiome by combining diversified culture conditions, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and 16S rRNA gene identification. The present study allowed identification of four putative new Clostridium sensu stricto species: 'Clostridium amazonitimonense' strain LF2(T), 'Clostridium massilidielmoense' strain MT26(T), 'Clostridium nigeriense' strain Marseille-P2414(T) and 'Clostridium merdae' strain Marseille-P2953(T), which we describe using the concept of taxonogenomics. We describe the main characteristics of each bacterium and present their complete genome sequence and annotation.

Keywords: human microbiota; emerging bacteria; 'Clostridium nigeriense'; 'Clostridium merdae'; culturomics; taxonogenomics; 'Clostridium amazonitimonense'; 'Clostridium massilidielmoense'

Domains: Life Sciences [q-bio]; Microbiology and Parasitology; Bacteriology; Life Sciences [q-bio]; Biodiversity; Systematics, Phylogenetics and taxonomy

M. T. Alou, S. Ndongo, L. Fregere, N. Labas, C. Andrieu, et al.. Taxonogenomic description of four new Clostridium species isolated from human gut : 'Clostridium amazonitimonense', 'Clostridium merdae', 'Clostridium massilidielmoense' and 'Clostridium nigeriense'.. New Microbes and New Infections, 2018, 21, pp.128-139. ⟨10.1016/j.nmni.2017.11.003⟩. ⟨hal-01795916⟩