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Genomic analysis of a Streptococcus pyogenes strain causing endocarditis in a child.

M. Beye 1 K. El Karkouri 1 N. Labas Didier Raoult 1 Pierre-Edouard Fournier 1
1 URMITE - Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes
Abstract : We sequenced the genome of Streptococcus pyogenes strain G773 that caused an infective endocarditis in a 4-year-old boy suffering from acute endocarditis. The 1.9-Mb genome exhibited a specific combination of virulence factors including a complete integrative and conjugative element, sp2905, previously described as incomplete in S. pyogenes, and five bacteriocin-coding genes. However, strain G773 lacked a CRISPR-Cas system.
Keywords : Endocarditis genome comparison real-time genome sequencing Streptococcus pyogenes virulence
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Submitted on : Friday, May 18, 2018 - 7:32:14 PM
Last modification on : Thursday, March 4, 2021 - 3:08:41 AM

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M. Beye, K. El Karkouri, N. Labas, Didier Raoult, Pierre-Edouard Fournier. Genomic analysis of a Streptococcus pyogenes strain causing endocarditis in a child.. New Microbes and New Infections, Wiley Online Library 2017, 17, pp.1--6. ⟨10.1016/j.nmni.2017.01.007⟩. ⟨hal-01795941⟩

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