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Lower Pregnancy Rates After IVF in Women Working as Occupational Cleaners A Preliminary Longitudinal Study

Abstract : OBJECTIVE: To assess clinical, biological, and environ­ mental factors influencing pregnancy rates (PRs) after in vitro fertilization (IVF), and to study the influence of occupational, lifestyle, and domestic exposure on PR. STUDY DESIGN: A longi­ tudinal cohort study was performed in women who started an IVF cycle with a self­administered question­ naire concerning their envi­ ronmental and occupation­ al exposure. Medical data were obtained from medical files. RESULTS: Among 534 cycles, we showed a variety of factors that had an impact on PR: age, infertility du­ ration, number of mature oocytes and embryos. After multivariate analysis, women with "elementary" occu­ pations had a significantly lower PR (OR 5.6; 95% CI 1.3-23.7). Among them, 82% were cleaners. CONCLUSION: This preliminary result leads us to focus on a socio­professional category that is already rec­ ognized in the literature as at risk for congenital abnor­ malities during pregnancy. Further cohort studies are needed to study the influence of socio­professional cate­ gory on PR.
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Submitted on : Friday, April 5, 2019 - 7:53:14 PM
Last modification on : Wednesday, August 19, 2020 - 12:08:22 PM

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  • HAL Id : hal-02091611, version 1

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Sabrina Soen, Jeanne Perrin, Irène Sari-Minodier, Elisabeth Jouve, Audrey Gnisci, et al.. Lower Pregnancy Rates After IVF in Women Working as Occupational Cleaners A Preliminary Longitudinal Study. The journal of Reproductive Medicine, 2018. ⟨hal-02091611⟩

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