Journal articles
De novo assembly of the complex genome of Nippostrongylus brasiliensis using MinION long reads
Abstract : Eukaryotic genome assembly remains a challenge in part due to the prevalence of complex DNA repeats. This is a particularly acute problem for holocentric nematodes because of the large number of satellite DNA sequences found throughout their genomes. These have been recalcitrant to most genome sequencing methods. At the same time, many nematodes are parasites and some represent a serious threat to human health. There is a pressing need for better molecular characterization of animal and plant parasitic nematodes. The advent of long-read DNA sequencing methods offers the promise of resolving complex genomes.
Cited literature [36 references]
https://hal-amu.archives-ouvertes.fr/hal-02094619
Contributor : Yves Bourne <>
Submitted on : Wednesday, April 24, 2019 - 11:41:45 AM
Last modification on : Tuesday, May 26, 2020 - 3:18:21 AM
Contributor : Yves Bourne <>
Submitted on : Wednesday, April 24, 2019 - 11:41:45 AM
Last modification on : Tuesday, May 26, 2020 - 3:18:21 AM
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De novo assembly of the comple...
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