Journal articles
Journal Pre-proof Cannabinoid exposure via lactation in rats disrupts perinatal programming of the GABA trajectory and select early-life behaviors
Abstract : Cannabis usage is increasing with its widespread legalization. Cannabis use by mothers during lactation transfers active cannabinoids to the developing offspring during this critical period and alters postnatal neurodevelopment. A key neurodevelopmental landmark is the excitatory to inhibitory gamma-aminobutyric acid (GABA) switch caused by reciprocal changes in expression ratios of the K+/Cl− transporters potassium-chloride cotransporter 2 (KCC2) and sodium-potassium-chloride transporter (NKCC1).
Cited literature [101 references]
https://hal-amu.archives-ouvertes.fr/hal-02389004
Contributor : Christophe Pellegrino Connect in order to contact the contributor
Submitted on : Monday, December 2, 2019 - 11:50:06 AM
Last modification on : Wednesday, November 3, 2021 - 4:40:16 AM
Long-term archiving on: : Tuesday, March 3, 2020 - 6:37:35 PM
Contributor : Christophe Pellegrino Connect in order to contact the contributor
Submitted on : Monday, December 2, 2019 - 11:50:06 AM
Last modification on : Wednesday, November 3, 2021 - 4:40:16 AM
Long-term archiving on: : Tuesday, March 3, 2020 - 6:37:35 PM